Abstract: Objective To investigate the value of dynamic enhanced computed tomography (CT) in diagnosis of hepatic sinusoidal obstructive syndrome (HSOS).Methods Fifty-one patients definitely diagnosed with HSOS, Budd-Chiari syndrome (BCS) and liver cirrhosis by biopsy or imaging were retrospectively analyzed. Dynamic enhanced CT and Baltimore standard were performed in these patients respectively, and comparisons were conducted. Results In HSOS patients, hepatomegaly and hypodensity were observed in non-contrastive CT scan. In terms of arterial phase on dynamic enhanced CT, it showed dilated and tortuous hepatic artery. And on the portal venous phase, it showed map-shaped change, unclear hepatic vein, inferior vena cava, portal vein with halo sign or track sign, flat inferior vena cava in the liver section, and etc. Additionally, enhanced range increased during delay period. In diagnosis of HSOS, CT was more sensitive than Baltimore standard (0.857 vs. 0.500), but less specific than Baltimore (0.811 vs. 0.946). Diagnostic accuracy of CT and Baltimore standard for HSOS was similar, which showed no statistically significant differences (P ＞ 0.05).Conclusion In early diagnosis of HSOS, CT dynamic enhanced is a powerful supplement to Baltimore standard, which is worth attention.

Key words: CT dynamic enhanced, Baltimore standard, Hepatic sinusoidal obstructive syndrome, Diagnosis