Abstract: Objective To study the genotypes and subtypes of hepatitis C virus (HCV) patients in Deyang area.Methods The baseline data and serum of patients infected with HCV in out hospital from January 2013 to July 2019 were collected. Viral genotyping was performed by reverse transcription-PCR fluorescent probe amplification technique. Chi-square test was used for data analysis.Results A total of 821 patients with HCV infection were included in this study. There were 7 genotypes and different subtypes including 1b, 2a, 3a, 3b, 6a, 1b+3b and 2a+3b among these patients, of which 1b accounted for 92.08% of all genotypes. There was no significant difference in the composition ratio between male and female patients between the genotypes (P>0.05). Among patients aged 40 years or younger, the proportions of genotypes 3a, 3b and 6a were significantly higher than those of patients older than 40 years, while the proportion of genotype 1b was lower than that of patients older than 40 years (P<0.05).Conclusion The major genotype of HCV in Deyang area is 1b. Genotypes 3 and 6 are more common in patients aged 40 years or younger.

Key words: Hepatitis C, Hepatitis C virus, Gene type, Distribution