Abstract: Objective To compare enhanced CT and magnetic resonance imaging (MRI) in the diagnosis of primary clear cell carcinoma in liver (PCCCL). Methods A total of 69 suspected PCCCL patients admitted to Suzhou Hospital of Integrated Traditional Chinese and Western Medicine from May 2020 to May 2022 were selected. All patients underwent enhanced CT and MRI examinations. The imaging features of enhanced CT and MRI were analyzed, and the detection efficacies of PCCCL by enhanced CT and MRI was compared by Kappa consistency analysis based on the pathological diagnosis of PCCCL. Results Among 69 suspected PCCCL patients, 59 were confirmed to have PCCCL after pathological diagnosis. The detection rate of enhanced CT for PCCCL was 62.32%, which hadn’t significant difference when compared with that of 75.36% by MRI (P>0.05). The total coincidence rate of enhanced CT in the diagnosis of PCCCL was 72.88% (43/59). After Kappa consistency analysis, the detection rate of enhanced CT had a good consistency with the pathological gold standard for the diagnosis of PCCCL (Kappa=0.438, P<0.05). The total coincidence rate of MRI diagnosis for PCCCLwas 88.14% (52/59), also shown good consistency with the pathological diagnosis (Kappa=0.714, P<0.05). The coincidence rate between MRI and gold standard in the diagnosis of PCCCL was 88.14%, which was higher than that of CT plain scan (72.88%) (χ²=4.374, P=0.036). The Yoden index of enhanced CT and MRI were 0.145 and 0.414, respectively. The sensitivity of MRI for the diagnosis of PCCCL was higher than that of enhanced CT, and the rate of misdiagnosis was lower than that of enhanced CT (P<0.05). Conclusion Both enhanced CT and MRI have certain reference value for the diagnosis of PCCCL, among which MRI has higher sensitivity and may reduce the occurrence of misdiagnosis.

Key words: Enhanced CT, Magnetic resonance imaging, Primary clear cell carcinoma of the liver, Diagnosis