Abstract: Objective To explore the application value of multi-slice spiral CT volu-me measurement of liver reserve function in patients with liver cirrhosis. Methods 42 healthy individuals who underwent liver reserve function examinations in Xuancheng City People's Hospital from June 2020 to June 2023 were selected as the normal group, while 42 patients with cirrhosis admitted during the same period were selected as the cirrhosis group. All patients underwent the multi-slice spiral CT volume measurement to analyze the corr-elation between liver reserve function and multi-slice spiral CT volume measurement value in patients with liver cirrhosis. Results Among 42 patients, there were 17 patients with Child Pugh grade A (40.48%), 18 patients with grade B (42.86%), and 7 patients with grade C (16.67%). The total liver volume [(1040.31±224.51)cm³], right lobe volume [(521.37±105.52)cm³], and left inner lobe volume [(150.85±45.18)cm³] in the cirrhosis group were lower than those in the normal group (total liver volume, 1408.62±158.57); (right lobe volume, 932.27±165.64); (left inner lobe volume, 224.19±43.67). The caudate lobe volume [(39.60±9.69)cm³] was higher than that in the normal group [(20.96±12.18)cm³,P<0.05]. The total liver volume [(1233.85±192.65)cm³], right lobe volume [(624.67±76.11)cm³] and left medial lobe volume [(179.51±47.96)cm³] in patients with grade A were higher than those in patients with grade B and C ( (total liver volume, 1028.52±164.61 and 899.33±141.55); (right lobe volume, 517.53±66.17 and 472.21±57.21); (left medial lobe volume, 154.96±33.77 and 129.91±31.12) ). The volume of caudate lobe [(30.30±6.15)cm³] was lower than that of patients with grade B and C [(39.47±6.02 and 46.11±6.12)cm³,P<0.05]. According to Kendall's tau-b correlation analysis, the total liver volume, right lobe volume, and left inner lobe volume of multi-slice spiral CT were positively correlated with the Child Pugh grade of patients with cirrhosis (r=0.325, 0.329, 0.256, P<0.05), while the measured volume of the caudate lobe by multi-slice spiral CT was negatively correlated with the Child Pugh grade in patients with cirrhosis (r=-0.396, P<0.05). The results of drawing receiver operating curve (ROC) curves showed that the area under the curve (AUC) of the total liver volume, right lobe volume, left inner lobe volume, caudate lobe volume, and combined measurement values for evaluating the Child-Pugh grading of liver function in patients with liver cirrhosis were all greater than 0.7, which had a certain evaluation value. Conclusion Multi-slice spiral CT measurement of total liver volume, right lobe volume, left inner lobe volume, and caudate lobe volume can be used to evaluate liver reserve function in patients with liver cirrhosis, and has certain evaluation value.

Key words: Multi-slice spiral CT, Volume measurement, Liver cirrhosis, Liver reserve function