[1] Gao B, Jeong W I, Tian Z. Liver: an organ with predominant innate immunity [J]. Hepatology, 2008, 47(2): 729-736.
[2] Murphy J M, Ngai L, Mortha A, et al. Tissue-dependent adaptations and functions of innate lymphoid cells [J]. Front Immunol, 2022, 13: 836999.
[3] Kim C H, Hashimoto-Hill S, Kim M. Migration and tissue tropism of innate lymphoid cells [J]. Trends Immunol, 2016, 37(1): 68-79.
[4] Peng H, Jiang X, Chen Y, et al. Liver-resident NK cells confer adaptive immunity in skin-contact inflammation [J]. J Clin Invest, 2013, 123(4): 1444-1456.
[5] Ghaedi M, Takei F. Innate lymphoid cell development [J]. J Allergy Clin Immunol, 2021, 147(5): 1549-1560.
[6] Lim A I, Verrier T, Vosshenrich C A, et al. Developmental options and functional plasticity of innate lymphoid cells [J]. Curr Opin Immunol, 2017, 44: 61-68.
[7] Wang X. Innate lymphoid cells originate from fetal liver–derived tissue-resident progenitors [J]. Science Immunology, 2025, 10.
[8] Daussy C, Faure F, Mayol K, et al. T-bet and eomes instruct the development of two distinct natural killer cell lineages in the liver and in the bone marrow [J]. Journal of Experimental Medicine, 2014, 211(3): 563-577.
[9] Fuchs A, Vermi W, Lee J S, et al. Intraepithelial type 1 innate lymphoid cells are a unique subset of IL-12- and IL-15-responsive IFN-gamma-producing cells [J]. Immunity, 2013, 38(4): 769-781.
[10] Bai L, Vienne M, Tang L, et al. Liver type 1 innate lymphoid cells develop locally via an interferon-γ–dependent loop [J]. Science, 2021, 371(6536).
[11] Jacquelot N, Seillet C, Souza-Fonseca-Guimaraes F, et al. Natural killer cells and type 1 innate lymphoid cells in hepatocellular carcinoma: current knowledge and future perspectives [J]. Int J Mol Sci, 2021, 22(16).
[12] Tang L, Peng H, Zhou J, et al. Differential phenotypic and functional properties of liver-resident NK cells and mucosal ILC1s [J]. J Autoimmun, 2016, 67: 29-35.
[13] Zhou J, Peng H, Li K, et al. Liver-resident NK cells control antiviral activity of hepatic T Cells via the PD-1-PD-L1 Axis [J]. Immunity, 2019, 50(2): 403-417.e404.
[14] Filipovic I, Sonnerborg I, Strunz B, et al. 29-color flow cytometry: unraveling human liver NK cell repertoire diversity [J]. Front Immunol, 2019, 10: 2692.
[15] Harmon C, Robinson M W, Fahey R, et al. Tissue-resident Eomes(hi) T-bet(lo) CD56(bright) NK cells with reduced proinflammatory potential are enriched in the adult human liver [J]. Eur J Immunol, 2016, 46(9): 2111-2120.
[16] Hydes T, Noll A, Salinas-Riester G, et al. IL-12 and IL-15 induce the expression of CXCR6 and CD49a on peripheral natural killer cells [J]. Immun Inflamm Dis, 2018, 6(1): 34-46.
[17] Lim A I, Menegatti S, Bustamante J, et al. IL-12 drives functional plasticity of human group 2 innate lymphoid cells [J]. J Exp Med, 2016, 213(4): 569-583.
[18] Cortez V S, Ulland T K, Cervantes-Barragan L, et al. SMAD4 impedes the conversion of NK cells into ILC1-like cells by curtailing non-canonical TGF-beta signaling [J]. Nat Immunol, 2017, 18(9): 995-1003.
[19] Krueger P D, Narayanan S, Surette F A, et al. Murine liver-resident group 1 innate lymphoid cells regulate optimal priming of anti-viral CD8+ T cells [J]. J Leukoc Biol, 2017, 101(1): 329-338.
[20] Thoens C, Berger C, Trippler M, et al. KIR2DL3(+)NKG2A(-) natural killer cells are associated with protection from productive hepatitis C virus infection in people who inject drugs [J]. J Hepatol, 2014, 61(3): 475-481.
[21] Doyle E H, Aloman C, El-Shamy A, et al. A subset of liver resident natural killer cells is expanded in hepatitis C-infected patients with better liver function [J]. Sci Rep, 2021, 11(1): 1551.
[22] Weizman O E, Adams N M, Schuster I S, et al. ILC1 confer early host protection at initial sites of viral infection [J]. Cell, 2017, 171(4): 795-808 e712.
[23] Picarda G, Ghosh R, McDonald B, et al. Cytomegalovirus evades TRAIL-mediated innate lymphoid cell 1 defenses [J]. J Virol, 2019, 93(16).
[24] Weizman O E, Song E, Adams N M, et al. Mouse cytomegalovirus-experienced ILC1s acquire a memory response dependent on the viral glycoprotein m12 [J]. Nat Immunol, 2019, 20(8): 1004-1011.
[25] Forrest C, Chase T J G, Cuff A O, et al. Control of human cytomegalovirus replication by liver resident natural killer cells [J]. Nat Commun, 2023, 14(1): 1409.
[26] Kang J, Liggett J R, Patil D, et al. Type 1 innate lymphoid cells are proinflammatory effector cells in ischemia-reperfusioninjury of steatotic livers [J]. Frontiers in Immunology, 2022, 13.
[27] Kojima H, Morinelli T A, Wang Y, et al. Group 1 innate lymphoid cells protect liver transplants from ischemia-reperfusion injury via an interferon gamma-mediated pathway [J]. Am J Transplant, 2025, 25(5): 969-984.
[28] Matsuda K, Ide N, Xu Y, et al. Type 1 innate lymphoid cell-immature neutrophil axis suppresses acute tissue inflammation [J]. Nat Commun, 2025, 16(1): 6574.
[29] Liu Y, Hu Y, Li B, et al. Innate lymphoid cell subsets in the pathogenesis of primary biliary cholangitis [J]. J Gastroenterol Hepatol, 2024, 39(7): 1431-1441.
[30] Zhao Z B, Lu F T, Ma H D, et al. Liver-resident NK cells suppress autoimmune cholangitis and limit the proliferation of CD4(+) T cells [J]. Cell Mol Immunol, 2020, 17(2): 178-189.
[31] Da T T, Liu M C, Bian Z H, et al. A novel subset of inflammation-related liver NK cells modulates immune responses in a murine model of primary biliary cholangitis [J]. J Autoimmun, 2025, 155: 103454.
[32] Nabekura T, Riggan L, Hildreth A D, et al. Type 1 innate lymphoid cells protect mice from acute liver injury via interferon-gamma secretion for upregulating Bcl-xL expression in hepatocytes [J]. Immunity, 2020, 52(1): 96-108 e109.
[33] Hildreth A D, Padilla E T, Tafti R Y, et al. Sterile liver injury induces a protective tissue-resident cDC1-ILC1 circuit through cDC1-intrinsic cGAS-STING-dependent IL-12 production [J]. Cell Rep, 2023, 42(2): 112141.
[34] Zhang H, Tang Q, Miao Y, et al. Group 1 innate lymphoid cell activation via recognition of NKG2D and liver resident macrophage MULT-1: Collaborated roles in triptolide induced hepatic immunotoxicity in mice [J]. Ecotoxicol Environ Saf, 2024, 272: 116072.
[35] Kudira R, Malinka T, Kohler A, et al. P2X1-regulated IL-22 secretion by innate lymphoid cells is required for efficient liver regeneration [J]. Hepatology, 2016, 63(6): 2004-2017.
[36] Liu T, Li J, Li Q, et al. Environmental eustress promotes liver regeneration through the sympathetic regulation of type 1 innate lymphoid cells to increase IL-22 in mice [J]. Hepatology, 2023, 78(1): 136-149.
[37] Wang R, Liang Q, Zhang Q, et al. Ccl2-induced regulatory T cells balance inflammation through macrophage polarization during liver reconstitution [J]. Adv Sci (Weinh), 2024, 11(45): e2403849. |
