Abstract: Objective To analyze the CT and MRI features of microvascular invasion in hepatocellular carcinoma and to evaluate its diagnostic value in hepatocellular carcinoma. Methods Forty-nine patients with hepatocellular carcinoma underwent CT or MRI plain and enhanced scan before operation. According to the pathological results, the patients were divided into positive group and negative group. The CT and MRI signs and diagnostic efficacy of the two groups were analyzed. Results 49 cases (61.25%) had microvascular infiltration lesions. Compared with negative group, the percentage of incomplete capsule, single nodule extranodal growth and continuous multiple nodules in positive group was significantly higher than that in negative group (P<0.05). The ADC value of the positive group was (1.261±0.263)×10^-3 mm²/s, and that of the negative group was (1.071±0.325)×10^-3 mm²/s. There was a significant difference between the two groups (P<0.05). Tumor morphology and ADC were the influencing factors of microvascular invasion (P<0.05). The diagnostic sensitivity and specificity of ADC value for microvascular invasion respectively were 75.00% and 87.50%. The diagnostic sensitivity and specificity of tumor morphology for microvascular invasion respectively were 91.67% and 75.00%. Conclusion Among the CT and MRI imaging features of hepatocellular carcinoma, tumor morphology and ADC value have high diagnostic efficiency for microvascular infiltration.