Abstract: Objective To evaluate the clinical value of three-dimensional reconstruction and hepatectomy simulation system in guiding right hemihepatectomy for tumor.Methods A retrospective analysis was made in 24 patients with primary hepatocellular carcinoma who underwent right hemihepatectomy from January 2017 to May 2018 in our hospital. These cases were randomly divided into 2 groups, 14 cases in three-dimensional reconstruction group and 10 cases in control group. The operation time, intraoperative blood loss, postoperative liver dysfunction, postoperative complications and hospitalization time after operation were recorded. Results The 2 groups successfully completed the operation without intraoperative complications such as massive hemorrhage. No complications such as hepatic dysfunction, hepatic failure, bile leakage occurred in three-dimensional reconstruction group after operation. In control group, only 1 case had transient hepatic insufficiency after operation. The operation time and postoperative hospitalization time were significantly shorter in three-dimensional reconstruction group than those in control group [(54.9±5.7) minutes vs. (73.7±7.3) minutes, (6.6±2.2) days vs. (8.5±1.9) days]. The intraoperative blood loss was significantly less in three-dimensional reconstruction group than that in control group [(124.3±25.2) ml vs. (248.0±65.9) ml]. And the postoperative alanine aminotransferase level was significantly lower in three-dimensional reconstruction group than that in control group [(124.3±25.2) U/L vs. (411.1±95.7) U/L].Conclusion Three-dimensional reconstruction and hepatectomy simulation system can accurately reconstruct the course of intrahepatic vessels and its anatomical relationship with tumors, and accurately display residual liver volume and tumor volume. It provides a reliable basis for surgical design of right hemihepatectomy for tumor, reduces the occurrence of intraoperative and postoperative complications, and shortens the hospitalization time of patients after operation. It has important clinical value for right hemihepatectomy for tumor.

Key words: Liver tumor, Right hemihepatectomy, Three-dimensional reconstruction, Clinical application