The noninvasive diagnostic models for primary biliary cirrhosis

Abstract

Abstract: Objective To verify the noninvasive diagnostic models of liver fibrosis in primary biliary cirrhosis (PBC), and to assess its diagnostic value on histologic staging. Methods Diagnostic value of the models on histologic staging was assessed by the receiver operating characteristic curve (AUC). Results The noninvasive diagnostic models had different levels of diagnostic values, especially H index, Forns Score and RPR, which could predict advanced fibrosis (stage III-IV) with an area under the receiver operating characteristic curve (AUROC) of 0.851, 0.811 and 0.843, respectively. Conclusion The noninvasive models of H index, Forns Score and RPR, which were consisting of laboratory markers, could help accurately identify early (stage I-II) and advanced (stage III-IV) liver fibrosis in patients with PBC.

Key words: Primary biliary cirrhosis, Noninvasive diagnostic model, Liver fibrosis

MA Jiali, LI Ping, ZHANG Fukui, ZHOU Yuling, LIANG Xiuxia, AI Zhenglin. The noninvasive diagnostic models for primary biliary cirrhosis[J]. Chinese Hepatolgy, 2016, 21(2): 105-106.

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