Chinese Hepatolgy ›› 2016, Vol. 21 ›› Issue (9): 719-721.

• Original Articles • Previous Articles     Next Articles

The clinical value of FibroScan for evaluating the hepatic fibrosis stage in patients with alcoholic liver disease

XU Wei   

  1. Department of Liver Disease, the Fifth People' Hospital of Wuxi, Jiangsu 214000, China
  • Received:2016-04-15 Online:2016-09-30 Published:2020-06-19

Abstract: Objective To investigate the clinical value of FibroScan for evaluating the hepatic fibrosis stage in patients with alcoholic liver disease. Methods In the study, 60 patients with alcoholic liver disease admitted in our hospital from June 2013 to June 2015 were enrolled. The liver stiffness was measured by FibroScan and quantified with FibroScan value, and liver biopsy was also conducted as the gold standard. The correlation between FibroScan value and the stage of hepatic fibrosis was analyzed by receiver operating characteristic (ROC) curve. Results The value of liver stiffness measured by FibroScan from stage 0 to stage 4 were 5.31±1.06, 7.91±2.81, 9.81±3.39, 14.66±4.31 and (19.81±6.02) kPa, respectively. The FibroScan value has a positive correlation with hepatic fibrosis stage in patients with alcoholic liver disease (r=0.706, P<0.05). The area under ROC for the patients with fibrosis stage ≥S1, ≥S2, ≥S3 and S4 was 0.833, 0.871, 0.906 and 0.919, respectively. Conclusion FibroScan could be used as a noninvasive technology to evaluate the hepatic fibrosis stage in patients with alcoholic liver disease.

Key words: Alcoholic liver disease, FibroScan, Hepatic fibrosis