Abstract: Objective To analyze the hemodynamic parameters from esophageal and gastric varices bleeding in cirrhosis.Methods The clinical data of 68 patients with liver cirrhosis complicated with esophagogastric varices diagnosed by Fujineng ultrasound gastroscopy in our hospital from October 2017 to April 2018 were retrospectively analyzed. Following up for half a year, the patients were divided into hemorrhage group and non-hemorrhage group according to whether there was venous rupture or not. There were 30 cases in hemorrhage group and 38 cases in non-hemorrhage group. The differences of sex, age, course of disease, the child-pugh score of liver function, platelet count, average diameter, average blood flow velocity measured by ultrasonography were compared between the two groups. Hemodynamic parameters affecting bleeding from esophageal and gastric varices in cirrhosis were analyzed. For closely related indicators, ROC curve was used to analyze the sensitivity and specificity. Results Eighty-six patients were followed up for half a year. 30 patients had venous rupture and bleeding, 56 patients had no bleeding. The bleeding rate of liver cirrhosis complicated with esophageal and gastric varices was 34.88%. The indexes of sex, age, course of disease, the Child-Pugh score of liver function(8.97±3.04), platelet count[(142.60±38.66)×10⁹/mL], average diameter[(1.54±0.62)mm], average blood flow velocity[(15.79±4.17)mm/s] were measured by ultrasound. Only the mean internal diameter, average blood flow velocity were closely related to the bleeding outcomes of gastric varices rupture (r=-0.294,-0.451,P<0.05). The other indicators were not related (P>0.05). ROC curve analysis showed that the internal diameter, average blood flow velocity were positively correlated with the bleeding outcome of gastric varices rupture, and the specificity and sensitivity has significant statistical significance (P<0.05). When the inner diameter of the varicose vein inside and outside the esophageal wall is larger than 1.875 mm, the average blood flow velocity exceeds 13.75mm/s, the gastric varices are more likely to rupture and bleed.Conclusion The internal diameter and blood flow velocity of esophageal varices are positively correlated with the bleeding outcomes of gastric varices rupture. Close monitoring of the internal diameter and blood flow velocity of esophageal varices should be carried out clinically, which is of great significance in preventing bleeding outcomes of gastric varices rupture and is worthy of clinical promotion.

Key words: Endoscopic ultrasonography, Liver cirrhosis, Esophageal and gastric varices, Hemodynamic parameters