Abstract: Objective To analyze the correlation between blood oxygen saturation and liver function abnormalities and clinical treatment in patients with COVID-19 novel coronavirus pneumonia. Methods Observe the incidence of abnormal liver function in 74 patients with confirmed COVID-19 new coronary pneumonia compared with mild/normal (46 cases) and severe/critical (28 cases) patients, as well as blood oxygen saturation and liver function biochemical indicators before and after treatment. Analyze the correlation between blood oxygen saturation and changes in biochemical indicators of liver function in patients as well. Results There were significant differences in oxygen saturation(96.52±1.68 VS 87.61±2.99), ALT(39.69±25.35 VS 57.25±37.89)、AST(61.00±17.66 VS 36.83±16.30)、LDH(61.00±17.66 VS 36.83±16.30) between mild/moderate and severe/critical patients (P<0.05);In the patients with abnormal liver function, blood oxygen saturation returned to normal after treatment, and liver function was restored to different degrees in both groups. ALT(66.82±21.65 VS 42.47±18.46)、AST (61.00±17.66 VS 36.83±16.30)、LDH(309.46±58.92 VS 218.38±45.12)of mild/normal patients, and ALT (93.54±21.06 VS 49.54±19.75), AST (57.93±14.22 VS 33.80±11.28)、LDH (329.79±54.78 VS 257.50±90.59) of severe/critical patients were significantly improved (P<0.05);In the correlation analysis with oxygen saturation, ALT, AST, r-GT and LDH were negatively correlated with oxygen saturation (P<0.05). Conclusion Low blood oxygen saturation in patients with new coronary pneumonia is closely related to abnormal liver function, and the restoration of blood oxygen saturation is helpful to improving liver function.

Key words: COVID-19 new coronavirus pneumonia, Oxygen saturation, Liver function