[1] Mederacke I, Hsu CC, Troeger JS, et al. Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology. Nat Commun, 2013, 4: 1-11.
[2] Affo S, Yu LX, Schwabe RF. The role of cancer-associated fibroblasts and fibrosis in liver cancer. Annu Rev Pathol, 2017,12:153-186.
[3] 闪雪纯,傅继华.肝纤维化分子机制及治疗靶点研究进展.医学研究与教育,2020,37:24-30.
[4] Xie X, Dou CY, Zhou Y, et al. MicroRNA-503 targets mothers against decapentaplegic homolog 7 enhancing hepatic stellate cell activation and hepatic fibrosis. Dig Dis Sci, 2020: 1-12.
[5] Fu X, Qie J, Fu Q, et al. miR-20a-5p/TGFBR2 axis affects pro-inflammatory macrophages and aggravates liver fibrosis. Front Oncol, 2020, 10: 107-115.
[6] Liang H, Wang X, Si C, et al. Downregulation of miR?141 deactivates hepatic stellate cells by targeting the PTEN/AKT/mTOR pathway. Int J Mol Med, 2020,46:406-414.
[7] Tao L, Wu L, Zhang W, et al. Peroxisome proliferator-activated receptor γ inhibits hepatic stellate cell activation regulated by miR-942 in chronic hepatitis B liver fibrosis. Life Sci, 2020, 253: 117572-117611.
[8] Li J, Dong S, Ye M, et al. MicroRNA-489-3p represses hepatic stellate cells activation by negatively regulating the JAG1/Notch3 signaling pathway. Dig Dis Sci, 2021,66:143-150.
[9] Wang Z, Zhao Y, Zhao H, et al. Inhibition of p66Shc oxidative signaling via CA-induced upregulation of miR-203a-3p alleviates liver fibrosis progression. Mol Ther Nucleic Acids, 2020,21:751-763.
[10] Wang YZ, Zhang W, Wang YH, et al. Repression of liver cirrhosis achieved by inhibitory effect of miR-454 on hepatic stellate cells activation and proliferation via Wnt10a. J Biochem, 2019,165:361-367.
[11] 葛善飞, 刘菲, 谢建萍. miRNAs调控肝星状细胞生物学活性机制研究进展. 山东医药, 2016,56:101-103.
[12] Hao XJ, Xu CZ, Wang JT, et al. miR-21 promotes proliferation and inhibits apoptosis of hepatic stellate cells through targeting PTEN/PI3K/AKT pathway. J Recept Signal Transduct Res, 2018,38:455-461.
[13] Niu X, Fu N, Du J, et al. miR-1273g-3p modulates activation and apoptosis of hepatic stellate cells by directly targeting PTEN in HCV-related liver fibrosis. FEBS Lett, 2016,590:2709-2724.
[14] Wang J, Chu ES, Chen HY, et al. microRNA-29b prevents liver fibrosis by attenuating hepatic stellate cell activation and inducing apoptosis through targeting PI3K/AKT pathway. Oncotarget, 2015,6:7325-7338.
[15] Wang Y, Du J, Niu X, et al. MiR-130a-3p attenuates activation and induces apoptosis of hepatic stellate cells in nonalcoholic fibrosing steatohepatitis by directly targeting TGFBR1 and TGFBR2. Cell Death Dis, 2017,8:e2792.
[16] Iredale JP. Models of liver fibrosis: exploring the dynamic nature of inflammation and repair in a solid organ. J Clin Invest, 2007, 117: 539-548.
[17] Poynard T, Lebray P, Ingiliz P, et al. Prevalence of liver fibrosis and risk factors in a general population using non-invasive biomarkers (FibroTest). BMC Gastroenterology, 2010, 10:40.
[18] Lam JK, Chow MY, Zhang Y, et al. siRNA versus miRNA as therapeutics for gene silencing. Mol Ther Nucleic Acids, 2015, 4: e252-e271.
[19] Friedman RC, Farh KK, Burge CB, et al. Most mammalian mRNAs are conserved targets of microRNAs. Genome Res, 2009,19:92-105.
[20] Lambrecht J, Verhulst S, Mannaerts I, et al. Prospects in non-invasive assessment of liver fibrosis: liquid biopsy as the future gold standard? Biochim Biophys Acta Mol Basis Dis, 2018, 1864: 1024-1036.
[21] 韦皓棠, 邓雅. 血液微小RNA在结直肠癌无创性筛查中应用的研究进展. 广西医学, 2020,42:2140-2143.
[22] 周艳齐, 赵松兰, 沈亚杰, 等. 宫颈癌患者外周血细胞中miRNA-216b的表达水平及临床意义. 癌症进展,2020,18:1668-1671.
[23] Teng KY, Barajas JM, Hu P, et al. Role of b cell lymphoma 2 in the regulation of liver fibrosis in mir-122 knockout mice. Biology (Basel), 2020, 9: 157-174.
[24] 吕金明, 李燕, 苏凤君. miRNA-122联合肿瘤标志物在慢性乙肝病毒感染肝硬化及早期肝癌诊断中的价值. 中华医院感染学杂志, 2020,30:2922-2926.
[25] 周兴蓓. 血清miRNA在慢性乙肝肝纤维化进展中的诊断价值. 江苏大学, 2019.
[26] Lambrecht J, Verhulst S, Reynaert H, et al. The miRFIB-Score: a serological miRNA-based scoring algorithm for the diagnosis of significant liver fibrosis. Cells, 2019, 8: 1003-1023.
[27] Lee YA, Wallace MC, Friedman SL. Pathobiology of liver fibrosis: a translational success story. Gut, 2015, 64: 830-841.
[28] Wu J, Huang J, Kuang S, et al. Synergistic microRNA therapy in liver fibrotic rat using MRI-visible nanocarrier targeting hepatic stellate cells. Adv Sci (Weinh), 2019, 6: 1801809-1801822.
[29] Zhu S, Wang T, Luo F, et al. Astaxanthin inhibits proliferation and induces apoptosis of LX-2 cells by regulating the miR-29b/Bcl-2 pathway. Mol Med Rep, 2019,19:3537-3547.
[30] 张利芬, 李彬彬, 余宏宇. MicroRNA-484通过靶向肝星状细胞中Fis1调控肝纤维化进程. 第二军医大学学报, 2017,38:1146-1151. |
