Chinese Hepatolgy ›› 2022, Vol. 27 ›› Issue (1): 51-53.

• Liver Fibrosis & Cirrhosis • Previous Articles     Next Articles

Application of ultrasonic measuring the diameter of vein in differentiating between schistosomiasis cirrhosis and hepatitis B cirrhosis

XIAO Kun1, LIU Ai-hua2, LIU Kun3   

  1. 1. Department of Ultrasound Imaging, Caidian District People's Hospital of Wuhan Xiehe Jiangbei Hospital, Wuhan 430100, Hubei Province, China;
    2. Department of Ultrasound Imaging, Jiangan District People's Hospital Affiliated to Jianghan University, Wuhan 430100, Hubei Province, China;
    3. Department of ultrasound, Zhongshan Hospital of Hubei, Hubei Province, China
  • Received:2021-06-25 Online:2022-01-31 Published:2022-02-11

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Abstract: Objective To investigate the application value of venous diameter measured by ultrasound in differentiating between schistosomiasis cirrhosis and hepatitis B cirrhosis.Methods A total of 78 patients with liver cirrhosis admitted to our hospital from August 2019 to August 2021 were included. Thirty-three cases were diagnosed as schistosomiasis cirrhosis and 45 cases were diagnosed as hepatitis B cirrhosis. Another 39 healthy volunteers who underwent physical examination in our hospital during the same period were also selected. Patients with schistosomiasis cirrhosis, patients with hepatitis B liver cirrhosis (before treatment) and healthy controls were all scanned by Siemens Acuson Sequoia 512 color Doppler ultrasound diagnostic apparatus to measure diameter of portal vein (DPV), diameter of splenic vein (DSV), diameter of superior mesenteric vein (DSMV). The DPV, DSPV and DSMV values of patients with schistosomiasis cirrhosis, patients with hepatitis B cirrhosis and healthy controls were compared. The value of DPV in diagnosing schistosomiasis cirrhosis and hepatitis B cirrhosis were analyzed by receiver operator characteristic (ROC) curve.Results The values of DPV, DSPV and DSMV in healthy controls were (10.4±1.8) mm, (7.1±1.1) mm, (6.9±2.4) mm, respectively. The values of DPV, DSPV and DSMV in patients with schistosomiasis cirrhosis were (11.9±2.6) mm, (9.3±2.2) mm, (10.7±2.0) mm, respectively. The values of DPV, DSPV and DSMV in patients with hepatitis B cirrhosis were (14.8±3.3) mm, (9.4±2.4) mm, (10.8±2.3) mm, respectively. The values of DPV, DSPV and DSMV of patients with schistosomiasis cirrhosis and patients with hepatitis B cirrhosis were significantly higher than those of healthy people (P<0.05). The DPV value of patients with schistosomiasis cirrhosis was significantly lower than that of patients with hepatitis B cirrhosis (P<0.05). ROC analysis showed that the area under the curve (AUC) of DPV in diagnosing schistosomiasis cirrhosis was 0.734, the standard error was 0.056, the 95% IC was 0.624 to 0.845, the best cutoff value was 10.750, the sensitivity was 0.822, the specificity was 0.590 (P<0.05). ROC analysis showed that the AUC of DPV in diagnosing hepatitis B cirrhosis was 0.825, the standard error was 0.053, the 95% IC was 0.722～0.928, the best cut-off value was 12.300, the sensitivity was 0.727, and the specificity was 0.923 (P<0.05).Conclusion Compared with healthy people, the DPV, DSPV and DSMV values of patients with schistosome cirrhosis and patients with hepatitis B cirrhosis are significantly higher. The DPV value between patients with schistosome cirrhosis and patients with hepatitis B cirrhosis is significantly different. ROC analysis confirmed that DPV can help diagnosing and differentiating the 2 diseases when the best cutoff values are 10.750 mm and 12.300 mm.

Key words: Schistosoma cirrhosis, Hepatitis B cirrhosis, Ultrasound, Differentiation, Diagnosis, Inner diameter of portal vein, Inner diameter of splenic vein, Inner diameter of superior mesenteric vein