Abstract: Objective To investigate the spiral computed tomography (CT) imaging features of primary clear cell carcinoma of liver (PCCCL). Methods The clinical and CT imaging data of 7 patients with PCCCL confirmed by pathology were collected and retrospectively analyzed. All the 7 cases underwent plain and dynamic enhanced CT scan. Results All the 7 cases of PCCCL were single lesions. Among them, 6 lesions located in the right lobe of liver, 1 lesion located in left lobe of liver. The diameter of tumor ranged from4 to 14 cm, with an average of 5.3 cm. Uneven low density and necrosis could be observed in 7 cases, and 2 cases with lipogenesis. There were 5 cases with clear boundary and pseudo-capsule, 2 cases with unclear boundary. Dynamic contrast-enhanced CT scans showed nonuniform enhancement in 7 cases. Enhancement in arterial phase and low density in venous phase were observed in 3 cases. Slight enhancement in arterial phase and continuous enhancement presented high density in venous phase were observed in 2 cases. The imaging of 2 cases showed nodular marked enhancement in arterial phase, progressive enhancement in venous phase and delayed phase, the extent of nodular enhancement gradually expanded. Conclusion There are some certain features in plain CT scan imaging of PCCCL, and the untypical enhancement features are related to the proportion of clear cell in the tumor. The characteristics of CT is valuable for the accurate diagnosis of PCCCL.

Key words: Liver neoplasm, Clear cell carcinoma of liver, X-ray computer tomography, Dynamic enhanced scanning