Abstract: Objective To understand the research hotspots and trends of anesthesia for liver transplantation between 2012 and 2021 through a bibliometric analysis.Methods The Web of Science (Core Collection) database was used as the statistical source. Literatures on anesthesia for liver transplantation were retrieved from 2012 to 2021. “The number of published articles per year , high-published journals, and high-cited papers” were analyzed by bibliometrics analysis. The VOSviewer software was used to analyze the co-occurrence cluster view and tag view of keywords.Results 469 documents on anesthesia for liver transplantation were included in this study. Statistics about anesthesia for liver transplantation researches changed from year to year a wavy trend within Web of Science lierature database. “TRANSPLANTATION PROCEEDINGS” was the primary source of literature. “Perioperative acute kidney injury” published in “BRITISH JOURNAL OF ANAESTHESIA” was the most cited article. Keywords co-occurrence cluster analysis of anesthesia for liver transplantation research hotspots included “organ protection of anesthetics”, “preoperative evaluation”, “liver transplantation combined with other organ transplantation”, “perioperative organ complications”, “pharmacology for anesthesia” and “perioperative volume management”. Also, “extracorporeal membrane-oxygen”, “thromboelastometry”, “hepatic ischemia”, “pain management”, “perioperative management” were getting more and more attention.Conclusion The current research hotspot on anesthesia for liver transplantation has shifted from basic research to research on the perioperative protection of organ function, which can provide scientific basis for the management of anesthesia for liver transplantation and improving postoperative survival rate.

Key words: Liver transplantation, Anesthesia, Bibliometric Analysis, VOSviewer