Chinese Hepatolgy ›› 2022, Vol. 27 ›› Issue (12): 1277-1279.

• Liver Fibrosis & Cirrhosis • Previous Articles     Next Articles

Relationship between quantitative parameters of high frequency ultrasound and liver function classification in patients with hepatitis B related cirrhosis

LIU Jian-xiang1, LI Yi-hui2, ZHAO Zi-yan3   

  1. 1. Department of Infection;
    2. Department of General Surgery, 921 Hospital of Joint Support Forces (The Second Affiliated Hospital of Hunan Normal University), Changsha 410022, China;
    3. Ruici Tianxin Outpatient Department Changsha Ruishang Health Management Co., Ltd., Hunan 410029, China
  • Received:2022-07-09 Published:2023-01-30

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Abstract: Objective To investigate the relationship between quantitative parameters of high frequency ultrasound and liver function classification in patients with hepatitis B cirrhosis.Methods A total of 105 hepatitis B cirrhosis patients were selected as hepatitis B cirrhosis group, and another 105 healthy cases who underwent physical examination in our hospital during the same period were selected as the control group. Both groups underwent high frequency ultrasound examination after admission, fasting and water-deprivation for 12 hours before examination. High frequency ultrasound examination was performed in supine position. After locating the defects in the image of liver parenchyma, the local maximum value per unit area of defect map was passed χ (D) Mean (d) of defect graph and entropy of defect graph ε (D) Quantitative evaluation of the degree of liver cirrhosis. The difference among χ (D), Mean (D) and ε (D) between the 2 groups were compared. According to the Child-pugh score, Child-pugh A, B and C was set as group A (n=41), group B (n=38), and group C (n=26), respectively. The quantitative parameters of high frequency ultrasound images of groups A, B and C were compared.Results The χ (D), mean (d) and ε (D) [(5.4 ± 2.5), (4.4 ± 2.3) and (4.5 ± 2.0)] of hepatitis B cirrhosis group were significantly higher than those of the control group [(2.8 ± 2.1), (2.0 ± 1.3) and (1.5 ± 0.9), P<0.05].The (d), mean (d) and ε (D) of group A was (4.7 ± 1.9), (3.9 ± 1.7) and (3.3 ± 1.5), group B (5.1 ± 2.5), (4.3 ± 1.9) and (3.7 ± 2.0), group C (4.5 ± 1.8), (3.7 ± 1.8) and (3.2 ± 1.5), respectively. The χ (D), mean (d) and ε (D) of group A were significantly lower than those of group B (P<0.05). But there was no significant difference among the parameters of group A and C, the same was true between group B and C.Conclusion Compared with healthy people, the texture parameters χ (D), mean (d) and ε (D) of patients with hepatitis B cirrhosis were significantly higher. There were significant differences in the above indicators between Child-Pugh grade A and B patients. The Child-Pugh A and B could be assessed by high frequency ultrasound, but Child-Pugh C level should be evaluated with other imaging features.

Key words: Chronic hepatitis B, Cirrhosis of the liver, Liver function, High frequency ultrasonic