Abstract: Objective To investigate the imaging features of multi-slice spiral computed tomography (MSCT) and blood biochemical indexes in patients with hepatitis B complicated with periportal effusion.Methods A total of 80 patients with chronic hepatitis B (CHB) admitted to our hospital from January 2018 to January 2021 were selected as the study subjects. All patients underwent MSCT examination. Patients were divided into observation group (51 cases with periportal effusion) and control group (29 cases without periportal effusion) according to the Results of MSCT. The MSCT manifestations of CHB patients with periportal effusion were observed. The blood biochemical indexes of glutamyl transpeptidase (GGT), aspartate aminotransferase (AST) and alanine aminotransferase (ALT) were compared between 2 groups.Results According to the Results of MSCT examination in observation group, effusion can be observed in the surrounding area of liver portal vein trunk and branches during portal venous phase. Low density shadow could be observed in the surrounding area of portal vein trunk and branches. The MSCT features of effusion around the portal vein were that: when scanning direction was parallel to the level and portal vein, the imaging feature was tramline sign, when the scanning plane was perpendicular to the portal vein, the imaging feature was target sign. The levels of GGT, AST and ALT in the observation group [(218.94 ± 36.52) U/L, (192.04 ± 31.75) U/L and (288.49 ± 52.74) U/L] were significantly higher than those in the control group [(174.58 ± 28.75) U/L, (158.62 ± 22.68) U/L and (229.37 ± 46.52) U/L], (P<0.05).Conclusion The imaging features of MSCT in CHB patients combined with periportal effusion were tramline sign or target signs. The degree of liver function injury in CHB patients with periportal effusion was higher than that in patients without portal effusion.

Key words: Hepatitis B, Periportal effusion, Liver function, Multislice spiral computed tomography