Chinese Hepatolgy ›› 2022, Vol. 27 ›› Issue (8): 895-897.

• Liver Cancer • Previous Articles     Next Articles

Comparison of the diagnostic value of multi-slice spiral CT and high field magnetic resonance LAVA enhancement in small hepatocellular carcinoma in the background of hepatitis B cirrhosis

XIE Hui1, WANG Liang-liang1, JIANG Kai2, YUAN Xiao1   

  1. 1. Department of Radiology, the People's Hospital of Suzhou New District, Jiangsu 215009,China;
    2. Department of imaging, Wuxi No.5 People's Hospital, Jiangsu 214007,China
  • Received:2022-03-18 Online:2022-08-31 Published:2022-09-30
  • Contact: YUAN Xiao, Email: yuanxiao3273@126.com

Abstract: Objective To compare the accuracy of multi-slice spiral CT and high field magnetic resonance imaging (MRI) liver acceleration volume acquisition (LAVA) in the diagnosis of small hepatocellular carcinoma (HCC) in the background of hepatitis B cirrhosis.Methods The clinical records of 72 patients with small HCC with hepatitis B cirrhosis background treated in our hospital from July 2019 to December 2021 were analyzed retrospectively. The diagnosis was confirmed by pathological test as the gold standard, and 100 patients with benign liver nodules with hepatitis B cirrhosis background were selected as control. The detection rates of multi-slice spiral CT and MRI in small HCC lesions and benign liver lesions were compared. ROC analysis was used to evaluate the diagnostic value of multi-slice spiral CT and MRI in small HCC.Results A total of 80 lesions were detected in 72 patients with small HCC in the background of hepatitis B cirrhosis. 65 and 74 lesions were detected by multi-slice spiral CT and MRI respectively. The detection rate of lesions by MRI was higher than that by multi-slice spiral CT (χ2=4.440, P=0.035). Among the 100 patients with benign liver lesions, there were 63 cases of hepatic cyst, 27 cases of hepatic hemangioma and 10 cases of hepatic inflammatory mass. 83 cases were detected by multi-slice spiral CT and 91 cases by MRI. There was no significant difference in the detection rate of benign liver lesions between the two groups (χ2=2.829, P=0.093). The positive rate of arterial phase in CT scan was higher than that in plain scan (P<0.05). The positive detection rate of arterial phase in MRI was higher than that in T2WI and T1WI (both P<0.05). MRI was more effective than CT in the diagnosis of small HCC (P<0.05).Conclusion Compared with multi-slice spiral CT scanning, the application of LAVA sequence in high field MRI scanning can more accurately diagnose small HCC.

Key words: Hepatitis B, Liver cirrhosis, small hepatocellular carcinoma, Multi slice spiral CT, High field magnetic resonance LAVA enhancement