Analysis of the efficacy of MRI and MSCT in the clinical diagnosis of intrahepatic cholangiocarcinoma

Abstract

Abstract: Objective Analyze the diagnostic value of magnetic resonance imaging (MRI) and multi-slice spiral computed tomography (MSCT) in detecting intrahepatic cholangiocarcinoma (ICC).Methods A total of 70 patients with primary liver cancer were admitted to our hospital between March 2017 and March 2022. All patients underwent MRI and MSCT examinations. The gold standard for diagnosis was postoperative histopathology examination and biopsy. If either MRI or MSCT diagnosed the patient with ICC, it was considered as ICC. We evaluated the efficacy of MRI, MSCT, and the combination of both in diagnosing ICC.Results Pathological diagnosis showed that out of the 70 patients with primary liver cancer, 23 were diagnosed with ICC and 47 with hepatocellular carcinoma (HCC).The MRI results identified 20 cases of ICC and 50 cases of HCC among the 70 cases of primary liver cancer. The sensitivity, specificity, accuracy, and Kappa value of MRI in diagnosing ICC were 69.6%, 91.5%, 84.3%, and 0.632, respectively. The MSCT identified 22 cases of ICC and 48 cases of HCC among the 70 cases of primary liver cancer. The sensitivity, specificity, accuracy, and Kappa value of MSCT in diagnosing ICC were 65.2%, 85.1%, 78.6%, and 0.509, respectively. The combined diagnostic results of MRI and MSCT showed that 21 cases were ICC and 49 cases were HCC among the 70 cases of primary liver cancer. The sensitivity, specificity, accuracy, and Kappa value of MRI combined with MSCT in diagnosing ICC were 82.6%, 95.7%, 91.4%, and 0.801, respectively. The accuracy of MRI and MSCT in diagnosing ICC was 59 cases (84.3%) and 54 cases (78.6%), respectively, with no statistically significant difference (P>0.05). However, the accuracy of MRI combined with MSCT in diagnosing ICC was significantly higher, with 67 cases (95.7%) (P<0.05).Conclusion MRI and MSCT are highly accurate in diagnosing ICC and show good consistency with pathological diagnosis. Furthermore, the combination of these two methods enhances the diagnostic value even further.

Key words: Intrahepatic cholangiocarcinoma, Hepatocellular carcinoma, Magnetic resonance imaging, Multi layer spiral computed tomography, diagnosis

CHENG Li, LI Jiang-shan, SUN Xiao-ling. Analysis of the efficacy of MRI and MSCT in the clinical diagnosis of intrahepatic cholangiocarcinoma[J]. Chinese Hepatolgy, 2023, 28(11): 1314-1318.

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