Abstract: Objective To investigate the effect of different blood supply types on the three-year efficacy of interventional embolism of patients diagnosed with hepatic hemangioma(HL). Methods A total of 75 HL patients admitted from July 2016 to July 2019 were enrolled as the study subjects and were divided into group A (rich blood supply, n=25), group B (moderate blood supply, n=28) and group C (deficient blood supply, n=22) according to the type of blood supply, and all patients underwent interventional embolism and were followed up for 3 years post-procedure. Clinical efficacy, maximum lesion diameter, and liver function metrics, including alanine aminotransferase (ALT) and total bilirubin (TBil)] levels, were compared among the three groups at 6, 12, and 36-month post-procedure. Results Compared with pre-operation measurements, the diameter of the lesion was significantly reduced post-operation in Group A (9.41±1.81, 5.71±0.94, 2.91±0.26, 2.74±0.21, respectively), Group B (9.52±1.87, 5.87±1.03, 3.29±0.38, 2.89±0.27, respectively), and Group C (9.39±1.87, 7.17±1.55, 6.53±0.78, 6.15±0.63, respectively) (P<0.05); The postoperative efficacy rates in Group A (64.00%, 80.00%, 88.00%) and Group B (64.29%, 67.86%, 78.57%) were notably higher than in Group C (22.73%, 31.82%, 31.82%). Moreover, the postoperative diameters of lesions in groups A and B were lower than that in group C (P<0.05). No significant differences were observed in ALT and TBIL among the three groups at different postoperative time points (P>0.05). Postoperative complications, such as nausea, vomiting, fever, and pain were reported in all three groups. The rich blood supply group reported 2 cases of Liver injury and one case of liver abscess. The moderate blood supply group reported 2 cases of liver injury and 1 case of biliary duct injury. The deficient blood supply group reported 2 cases of liver injury, and all complications were successfully managed with symptomatic treatment. Conclusion The therapeutic effect of interventional embolization varies among HL patients with different types of blood supply. Specifically, patients with a rich or moderate blood supply tend to experience therapeutic outcomes, while those with a deficient blood supply have less favorable results. However, the type of blood supply does not appear to influence the complications or liver function in HL patients following interventional embolization.

Key words: Blood supply type, Hepatic hemangioma, Interventional embolization, Liver function