Analysis of etiology, clinical features and prognosis of hepatic myelopathy

Abstract

Abstract: Objective To explore the etiology, clinical features and prognosis of hepatic myelopathy (HM). Methods Forty-nine patients with liver cirrhosis admitted to Baotou Mongolian Traditional Chinese Medicine Hospital between April 2016 and May 2022 were divided into HM group (n=24) and non-HM group (n=25) according to the presence of HM. HM group was divided into improvement group (n=6) and non-improvement group (n=18) according to prognosis. The etiologies of HM patients and non-HM patients were compared and the clinical data of improvement group and non-improvement group were compared. Methods There was no significant difference when comparing the etiology of HM patients with that of non-HM patients. Hepatitis B was the most common cause of HM (54.2%). Comparing the clinical data of the patients in the improvement group and the non-improvement group, the CHE level and the proportion of Child-Pugh grade B in the improvement group were (3597.7±1194.5) U/L and 83.3% respectively, which were significantly higher than that of non-improvement group [(1953.8±863.4) U/L and 22.2%]. Conclusion Hepatitis B is the most common cause of HM, and decreased muscle strength is the most common clinical manifestation in patients with hepatic myelopathy. CHE level and Child-Pugh grade may reflect the prognosis of patients.

Key words: Hepatic myelopathy, Etiology, Prognosis

Sudbayan er Subuda, WU Xi-de, Udungova. Analysis of etiology, clinical features and prognosis of hepatic myelopathy[J]. Chinese Hepatolgy, 2025, 30(1): 74-77.

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