Abstract: Objective To analyze the typical characteristics of patients with diabetes complicated by bacterial liver abscess and the curative effect of follow-up treatment, so as to provide basis for clinical diagnosis and treatment. Methods A total of 117 patients with bacterial liver abscess who were admitted to Changzhi People 's Hospital Affiliated to Changzhi Medical between November 2019 and May 2023 were included in the study. Patients were divided into two groups based on the presence or absence of diabetes: a diabetic group (n=44) and a non-diabetic group (n=73). The general data, laboratory examination and imaging examination of patients were compared, and the curative effect was evaluated after observation and follow-up. Results Comparing the general data, it was observed that the proportions of chills and abdominal pain in the diabetic group were 43.2% and 65.9% respectively, which were significantly higher than those in the non-diabetic group [23.3% and 35.6% (P<0.05)]; comparing the imaging results, it can be seen that the proportion of patients with multiple abscesses and the proportion of abscesses with a maximum diameter greater than 10cm in the diabetic group were 34.2% and 54.5%, which were significantly higher than those in the non-diabetic group [11.4% and 20.5% (P<0.05)]. The proportion of abscesses with a maximum diameter less than 5cm was 6.8%, significantly lower than the patients in the non-diabetic group (30.1%) (P<0.05); Comparing the laboratory test results, it can be seen that the levels of ALT, AST and TBil in the diabetic group were 247.5 (84.5, 644.9) U/L and 314.1 (164.5, 164.5, respectively). 766.2) U/L and 68.2 (42.7, 135.8) μmol/L, which were significantly higher than those in the non-diabetic group [48.2 (12.3, 134.1) U/L, 42.9 (15.3, 164.5) U/L and 35.1 (10.2, 59.3 ) μmol/L (P<0.05)]; Comparing the efficacy, it can be seen that the procalcitonin recovery time, intravenous antibiotic use time and hospitalization time of more than three weeks in the diabetes group were 8.5 (5.5, 10.5) days and 18.5 (12.0, 12.0, respectively). 22.0) days and 45.5%, which were significantly higher than the non-diabetic group [4.5 (2.5, 6.0) days, 10.0 (8.0, 16.0) days and 21.9% (P<0.05)]. Conclusion Patients with bacterial liver abscess complicated by diabetes have more diverse and severe symptoms and poorer treatment efficacy.

Key words: Diabetes, Bacterial liver abscess, Clinical efficacy