Abstract: Objective To explore the clinical and imaging features of hepatic confluent fibrosis (CF) in order to increase the diagnostic experience and awareness of the disease. Methods The clinical and imaging data of 19 patients with hepatic confluent fibrosis confirmed by imaging and puncture pathology from October 2023 to October 2024 in the fifth medical center of PLA general hospital were analyzed, and the general data, etiological types and imaging characteristics of the patients were sorted out and summarized. Results The clinical symptoms of 19 CF patients were mainly liver function abnormalities, fatigue, abdominal distension and abdominal pain. 8 patients were drug-induced liver damage and 6 patients were autoimmune liver diseases who were diagnosed by pathology. MR enhanced abdominal scan images showed that 18 patients were single lesions, and lesions were located in the right lobe of the liver in 15 patients. In 6 patients, the liver volume decreased and wrinkling of the liver capsule was seen. The enhancement mode was progressive enhancement, with no obvious enhancement in the arterial stage, and the high signal in the portal stage and delay stage was relatively obvious. Conclusion CF is more common in middle-aged and old women, without specific clinical symptoms, The main pathogenic factors are mainly drug-induced or autoimmune damage, MR images usually show wedge lesions and progressive enhancement pattern, which is not easy to diagnose when showing mass appearance. The combination of clinical history and imaging findings may help to diagnose CF, and pathological results may provide accurate result when the diagnosis is difficult.

Key words: Liver, Magnetic resonance imaging, Tomography, Fibrosis, Ultrasound