Analysis of therapeutic effects of ultrasound-guided percutaneous liver puncture and catheterization drainage in the treatment of patients with bacterial liver abscess

Abstract

Abstract: Objective To analyze the effects of ultrasound-guided percutaneous hepatic puncture for pus extraction and tube placement for drainage on the therapeutic efficacy of patients with bacterial liver abscesses. Methods 80 patients with bacterial liver abscesses treated in our hospital from 2020.10 to 2023.4 were enrolled in this study, prospectively. Patients were divided into a control group (34 cases, ultrasound-guided percutaneous hepatic puncture for pus extraction) and an observation group (46 cases, ultrasound-guided percutaneous hepatic puncture for drainage) according to the randomized numerical method. Clinical efficacy, symptom improvement, inflammatory indicators, and complication rates were compared between the 2 groups. Results Clinical efficacy in the control group was 88.2% , lower than 91.3% in the observation group; the recovery time of body temperature, the disappearance time of pain, and the disappearance time of abscess were (3.0±0.7) d, (2.8±0.6) d, and (12.6±2.0) d, respectively, as for the observation group, the recovery time of body temperature, the disappearance time of pain, and the disappearance time of abscess were (3.1±0.8) d, (2.7±0.6) d, and (12.8±2.2) d, respectively; the serum interleukin-6 (IL-6), interleukin-8 (IL-8), and tumor necrosis factor-α (TNF-α) levels in the control group after treatment were (21.9±3.4) ng/mL, (25.3±3.9) ng/mL, (8.6±1.5) ng/mL, respectively, higher than (22.1±3.5) ng/mL, (25.7±3.9) ng/mL, and (8.9±1.6) ng/mL in the observation group; the total complication rate of the control group was 17.7% , and the total complication rate of the observation group was 20.6%, there was no difference between two groups (P>0.05). Conclusion Ultrasound-guided percutaneous hepatic puncture to extract pus and tube drainage exhibited good efficacy in the treatment of patients with bacterial liver abscess, which can improve clinical symptoms, reduce the level of inflammatory factors, and have good safety, worthy to be selected as clinical treament according to the patient′s condition.

Key words: Bacterial liver abscess, Ultrasound guidance, Puncture aspiration for pus, Catheterization and drainage

YANG Zheng-fang, QI Jia-gao, ZHANG Fu-qun, WANG Yuan. Analysis of therapeutic effects of ultrasound-guided percutaneous liver puncture and catheterization drainage in the treatment of patients with bacterial liver abscess[J]. Chinese Hepatolgy, 2025, 30(7): 979-982.

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