Abstract: Objective To investigate the risk factors of material satisfaction in percutaneous needle biopsy. Methods The risk factors of ultrasound-guided percutaneous liver biopsy cases of Jiawang District People′s Hospital, Xuzhou city from January 2022 to June 2023, were retrospectively analyzed. The following factors, age, size and site of lesion, number of puncture, and presence of necrosis in the lesion, were analyzed. Biopsy satisfaction was analyzed by the diagnosis. Safety was analyzed by the percentage of complications classified as serious and minor complications. Results 80 patients had 87 biopsies taken. 91.3% (73/80) of the biopsies were malignant, and 62.5% (50/80) of the lesions were located in the right lobe of the liver. The median number of tissue columns obtained from biopsy was 3 (range 1 to 6); 91.3% (73/80) had satisfactory biopsy material with low lesion necrosis. Complications were noted in 7 (8.8%) patients, including 3 (3.8%) patients of major complication (2 bleeding and 1 infection), and 4 (5.0%) patients of minor complications. Patients with lesion necrosis, malignant lesions, left-lobe lesions, and multiple punctures had a higher incidence of complications (P<0.05). Conclusion Ultrasound-guided percutaneous liver biopsy is a safe and effective technique for histological diagnosis of liver lesions, including necrosis, malignant lesions and increased incidence of complications. Lesion diameter and necrosis affected biopsy satisfaction.

Key words: Biopsy, Ultrasonic guidance, Liver space, Risk factor