Value of CT dynamic contrast-enhanced imaging combined with ultrasound-guided liver biopsy in diagnosing hepatic space-occupying lesions

Abstract

Abstract: Objective To investigate the diagnostic value of CT dynamic contrast-enhanced imaging combined with ultrasound-guided liver biopsy in diagnosing hepatic space-occupying lesions. Methods Between November 2020 and November 2024, 95 patients with malignant hepatic space-occupying lesions were encountered in Jieshou People′s Hospital. All patients underwent ultrasound-guided liver biopsy. Based on whether they received CT dynamic contrast-enhanced scanning, tissue strip lengths and test results were compared between the two groups. Results Among the 95 patients with malignant hepatic space-occupying lesions in this group, 55 patients received CT dynamic contrast-enhanced scanning (the observation group), and 40 patients did not (the control group). In the control group, 5 patients had bleeding, all of which were exudative. After compression for self-hemostasis, they returned to normal. No bleeding was observed in the observation group (χ²=7.257, P=0.007). The lengths of effective pathological tissue strips in the control group and the observation group were (15.84±2.02) mm and (17.62±2.31) mm respectively. The length in the observation group was longer than that in the control group (t=3.975, P<0.001). The positive rate of diagnosis by ultrasound-guided biopsy in the control group was 75.00% (30/40). The positive rate of diagnosis by CT dynamic contrast-enhanced scanning combined with ultrasound-guided biopsy in the observation group was 92.73% (51/55). The detection accuracy of the observation group was higher than that of the control group, and the difference was statistically significant (χ²=5.792, P=0.016). Conclusion CT dynamic contrast-enhanced scanning combined with ultrasound-guided liver biopsy for the diagnosis of hepatic space-occupying lesions can reduce the patient′s bleeding risk and improve the diagnostic accuracy.

Key words: CT dynamic contrast-enhanced scanning, Ultrasound-guided liver biopsy, Hepatic space-occupying lesions, Diagnostic efficacy

LI Jia-shan, DU Yun-song, MA Meng, SONG Yan. Value of CT dynamic contrast-enhanced imaging combined with ultrasound-guided liver biopsy in diagnosing hepatic space-occupying lesions[J]. Chinese Hepatolgy, 2026, 31(4): 525-527.

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