Comparison of the efficacy between ultrasound-guided percutaneous liver abscess aspiration and catheter drainage in treating type 2 diabetes mellitus complicated with liver abscess

Abstract

Abstract: Objective To compare the efficacy of ultrasound-guided percutaneous liver abscess aspiration versus catheter drainage in treating type 2 diabetes mellitus (T2DM) complicated with liver abscess. Methods A total of 83 patients with T2DM complicated by liver abscess admitted to our hospital between June 2021 and March 2025 were divided into an observation group (n=41, aspiration) and a control group (n=42, drainage) based on the intervention. Perioperative indicators, liver function, WBC counts, inflammatory cytokines, and complications in our study were compared between two groups. Results The observation group showed significantly shorter recovery times of body temperature (3.4±1.2) days, WBC normalization (4.3±1.3) days, liver pain resolution (1.2±0.5) days, and abscess cavity disappearance (7.2±1.5) days compared to the control group [(3.7±1.4) days, (6.2±1.0) days, (1.5±0.6) days, and (10.5±2.8) days, respectively; P<0.05]. After 1 week of treatment, liver function were improved significantly in both groups (P<0.05), but no intergroup differences were observed in ALT, AST, or Alb levels before or after treatment (P>0.05). Similarly, WBC, IL-6, PCT, and TNF-α levels decreased significantly post-treatment (P<0.05), with no intergroup differences (P>0.05). Complications (e.g., hemorrhage, hematoma, incision infection, bile leakage, biliary peritonitis, pneumothorax) occurred in 3 cases (7.3%) in the observation group were significantly lower than the control group [10 cases (23.8%), P<0.05]. Conclusion Ultrasound-guided percutaneous liver puncture and pus aspiration can relieve clinical symptoms more quickly and promote the disappearance of pus cavity, and has a lower incidence of complications than catheter drainage.

Key words: Liver abscess, Type 2 diabetes mellitus, Ultrasound-guided percutaneous liver abscess aspiration

XU Teng-yun, ZHU Mei-di, KAN Xiao-chun, CHEN Chao-bo. Comparison of the efficacy between ultrasound-guided percutaneous liver abscess aspiration and catheter drainage in treating type 2 diabetes mellitus complicated with liver abscess[J]. Chinese Hepatolgy, 2025, 30(12): 1710-1713.

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