[1] Takahashi K,Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell,2006,126: 663-676. [2] Okita K,Ichisaka T,Yamanaka S.Generation of germline-competent induced pluripotent stem cells. Nature,2007,448: 313-317. [3] Imamura M,Hikabe O,Lin ZY,et al. Generation of germ cells in vitro in the era of induced pluripotent stem cells. Mol Reprod Dev,2014,81:2-19. [4] Compagnucci C,Petrini S,Higuraschi N,et al. Characterizing PCDH19 in human induced pluripotent stem cells (iPSCs) and iPSC-derived developing neurons: emerging role of a protein involved in controlling polarity during neurogenesis. Oncotarget,2015,6:26804-26813. [5] Huang NF,Dewi RE,Okogbaa J,et al. Chemotaxis of human induced pluripotent stem cell-derived endothelial cells. Am J Transl Res,2013,5:510-520. [6] Zhang L,Pan Y,Qin G,et al. Inhibition of stearoyl-coA desaturase selectively eliminates tumorigenic Nanog-positive cells: improving the safety of iPS cell transplantation to myocardium. Cell Cycle,2014,13:762-771. [7] Chiang CH,Chang CC,Huang HC,et al. Investigation of hepatoprotective activity of induced pluripotent stem cells in the mouse model of liver injury. J Biomed Biotechnol,2011,2011:219060. [8] Bilic J,Izpisua Belmonte JC. Concise review: Induced pluripotent stem cells versus embryonic stem cells: close enough or yet too far apart? Stem cells,2012,30:33-41. [9] Cao S,Loh K,Pei Y,et al. Overcoming barriers to the clinical utilization of iPSCs: reprogramming efficiency, safety and quality. Protein Cell,2012,3:834-845. [10] Diagnostic and treatment guidelines for liver failure(2012 version). Zhonghua Gan Zang Bing Za Zhi,2013,21:177-183. [11] Byam J,Renz J,Millis JM. Liver transplantation for hepatocellular carcinoma. Hepatobiliary Surg Nutr,2013,2:22-30. [12] Tian L,Prasad N, Jang YY. In vitro modeling of alcohol-induced liver injury using human-induced pluripotent stem cells. Methods Mol Biol,2016,1353:271-283. [13] Liu H,Kim Y,Sharkis S,et al. In vivo liver regeneration potential of human induced pluripotent stem cells from diverse origins. Sci Transl Med,2011,3:82ra39. [14] Takebe T,Zhang RR,Koike H,et al. Generation of a vascularized and functional human liver from an iPSC-derived organ bud transplant. Nat Protoc,2014,9:396-409. [15] Habib O,Habib G,Choi HW,et al. An improved method for the derivation of high quality iPSCs in the absence of c-Myc. Exp Cell Res,2013,319:3190-3200. [16] Nakagawa M,Koyanagi M,Tanabe K,et al. Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts. Nat Biotechnol.,2008,26:101-106. [17] Driscoll TP,Cosgrove BD,Heo SJ,et al. Cytoskeletal to nuclear strain transfer regulates YAP signaling in mesenchymal stem cells. Biophys J,2015,108:2783-2793. [18] Ohgushi M,Minaguchi M,Sasai Y. Rho-signaling-directed YAP/TAZ activity underlies the long-term survival and expansion of human embryonic stem cells. Cell Stem Cell,2015,17:448-461. [19] Cooray S,Howe SJ,Thrasher AJ. Retrovirus and lentivirus vector design and methods of cell conditioning. Methods Enzymol. 2012,507:29-57. [20] Narazaki G,Uosaki H,Teranishi M,et al. Directed and systematic differentiation of cardiovascular cells from mouse induced pluripotent stem cells. Circulation,2008,118:498-506. [21] Segura MM,Garnier A,Durocher Y,et al. New protocol for lentiviral vector mass production. Methods Mol Biol,2010,614:39-52. [22] Margariti A,Winkler B,Karamariti E,et al. Direct reprogramming of fibroblasts into endothelial cells capable of angiogenesis and reendothelialization in tissue-engineered vessels. Proc Natl Acad Sci USA,2012,109:13793-13798. [23] Han D,Byun SH,Park S,et al. YAP/TAZ enhance mammalian embryonic neural stem cell characteristics in a Tead-dependent manner. Biochem Biophys Res Commun. 2015,458:110-116. [24] Polanco JC,Ho MS,Wang B,et al. Identification of unsafe human induced pluripotent stem cell lines using a robust surrogate assay for pluripotency. Stem Cells,2013,31:1498-1510. [25] Huang J,Kalderon D. Coupling of Hedgehog and Hippo pathways promotes stem cell maintenance by stimulating proliferation. J Cell Biol,2014,205:325-338. [26] Ben-David U,Gan QF,Golan-Lev T,et al. Selective elimination of human pluripotent stem cells by an oleate synthesis inhibitor discovered in a high-throughput screen. Cell Stem Cell,2013,12:167-179. [27] Chang HM,Liao YW,Chiang CH,et al. Improvement of carbon tetrachloride-induced acute hepatic failure by transplantation of induced pluripotent stem cells without reprogramming factor c-Myc. Int J Mol Sci,2012,13:3598-3617. [28] Chiang CH,Wu WW,Li HY,et al. Enhanced antioxidant capacity of dental pulp-derived iPSC-differentiated hepatocytes and liver regeneration by injectable HGF-releasing hydrogel in fulminant hepatic failure. Cell Transplant,2015,24:541-559. [29] Zhang RR,Takebe T,Miyazaki L,et al. Efficient hepatic differentiation of human induced pluripotent stem cells in a three-dimensional microscale culture. Methods Mol Biol,2014,1210:131-141. [30] Choi SM,Kim Y,Liu H,et al. Liver engraftment potential of hepatic cells derived from patient-specific induced pluripotent stem cells. Cell Cycle,2011,10:2423-2427. [31] Chen YF,Tseng CY,Wang HW,et al. Rapid generation of mature hepatocyte-like cells from human induced pluripotent stem cells by an efficient three-step protocol. Hepatology,2012,55:1193-1203. [32] Chien Y,Chang YL,Li HY,et al. Synergistic effects of carboxymethyl-hexanoyl chitosan, cationic polyurethane-short branch PEI in miR122 gene delivery: accelerated differentiation of iPSCs into mature hepatocyte-like cells and improved stem cell therapy in a hepatic failure model. Acta Biomater,2015,13:228-244. [33] Nagamoto Y,Takayama K,Tashiro K,et al. Efficient engraftment of human induced pluripotent stem cell-derived hepatocyte-like cells in uPA/SCID mice by overexpression of FNK, a Bcl-xL Mutant Gene. Cell Transplant,2015,24:1127-1138. [34] Ramanathan R,Pettinato G,Beeston JT,et al. Transplantation of human stem cell-derived hepatocytes in an animal model of acute liver failure. Surgery,2015,158:349-359. [35] Zhang R,Takebe T,Sekine K,et al. Identification of proliferating human hepatic cells from human induced pluripotent stem cells. Transplant Proc,2014,46:1201-1204. [36] Takebe T,Sekine K,Enomura M,et al. Vascularized and functional human liver from an iPSC-derived organ bud transplant. Nature,2013,499:481-484. [37] Lau TT,Ho LW,Wang DA. Hepatogenesis of murine induced pluripotent stem cells in 3D micro-cavitary hydrogel system for liver regeneration. Biomaterials,2013,34:6659-6669. |