关键词: 肝内胆管囊腺癌, 磁共振成像, 体层摄影术

Abstract: Objective To analyze the clinical and imaging features of intrahepatic biliary cystadenocarcinoma (IBC). Methods The clinical data of 10 patients with IBC hospitalized in our hospital from October 2010 to December 2019 were analyzed retrospectively. The main complaints, clinical manifestations, laboratory examination and imaging features were summarized. Results In 10 patients with IBC, abdominal pain and abdominal distension were the main symptoms. There were 5 cases with no increased tumor markers, 3 cases with increased cancer antigen (CA) 125, 4 cases with increased CA199, 2 cases with increased carcinoembryonic antigen (CEA), and 1 case with increased CA724. Computed tomography (CT) or magnetic resonance (MR) showed cystic solid lesions with a long diameter of 1.50 cm-11.10 cm in 8 cases, mild to obvious intrahepatic bile duct dilatation around the lesions in 7 cases, wall nodules in 7 cases, irregular separation and septal enhancement in 6 cases, and progressive enhancement in 8 cases. Lymph node metastasis was found in 4 patients. And multiple metastases were found on MR and CT in 1 patient 1 year after operation. Conclusion IBC is more common in middle-aged and elderly women. The main clinical manifestations are abdominal pain and abdominal distention. Some patients may have elevated CA199 and CA125. The imaging findings are characterized with cystic solid masses with clear boundaries, sometimes with wall nodules, bile duct dilatation, irregular separation and progressive enhancement. Metastasis can occur in some patients, and the treatment should be complete surgical resection.

Key words: Intrahepatic biliary cystadenocarcinoma, Magnetic resonance imaging, Computed tomography