[1] 中华医学会肝病学分会脂肪肝和酒精性肝病学组, 中国医师协会脂肪性肝病专家委员会. 非酒精性脂肪性肝病防治指南(2018更新版). 实用肝脏病杂志,2018, 21:177-186.
[2] 薛芮, 范建高.代谢相关脂肪性肝病新定义的国际专家共识简介.实用肝脏病杂志,2020,23:457-460.
[3] Cerk IK, Wechselberger L, Oberer M. Adipose Triglyceride Lipase Regulation: An Overview. Curr Protein Pept Sci,2018,19:221-233.
[4] Zechner R, Zimmermann R, Eichmann TO, et al. FAT SIGNALS--lipases and lipolysis in lipid metabolism and signaling. Cell Metab,2012; 15:279-291.
[5] Lord CC, Ferguson D, Thomas G, et al. Metabolism does not require ATGL co-activation. Cell Rep,2016,16:939-949.
[6] Ong KT, Mashek MT, Bu SY, et al. Hepatic ATGL knockdown uncouples glucose intolerance from liver TAG accumulation. FASEB J,2013,27:313-321.
[7] Ong KT, Mashek MT, Bu SY, et al. Adipose triglyceride lipase is a major hepatic lipase that regulates triacylglycerol turnover and fatty acid signaling and partitioning. Hepatology,2011,53:116-126.
[8] Jenkins CM,Maneuso DJ,Yan W,et a1.Identification,cloning, expression.and purification of three novel human catcium— independent phospholipase A2 family members possessing triaeylglycerol lipase and acylglyeerol transaeylase activities.J Biol Chem,2004,279:48968-48975.
[9] Dubuquoy C, Robichon C, Lasnier F, et al. Distinct regulation of adiponutrin/PNPLA3 gene expression by the transcription factors ChREBP and SREBP1c in mouse and human hepatocytes. J Hepatol,2011,55:145-153.
[10] Huang Y, He S, Li JZ, et al. A feed-forward loop amplifies nutritional regulation of PNPLA3. Proc Natl Acad Sci U S A,2010,107:7892-7897.
[11] Chen W, Chang B, Li L, et al. Patatin-like phospholipase domain-containing 3/adiponutrin deficiency in mice is not associated with fatty liver disease. Hepatology, 2010,52:1134-1142.
[12] Liu YL, Patman GL, Leathart JB, et al. Carriage of the PNPLA3 rs738409 C>G polymorphism confers an increased risk of non-alcoholic fatty liver disease associated hepatocellular carcinoma. J Hepatol,2014,61:75-81.
[13] Chromy D, Mandorfer M, Bucsics T, et al. Prevalence and predictors of hepatic steatosis in patients with HIV/HCV coinfection and the impact of HCV eradication. AIDS Patient Care STDS,2019, 33:197-206.
[14] St?ttermayer AF, Traussnigg S, Dienes HP, et al. Hepatic steatosis in Wilson disease - role of copper and PNPLA3 mutations. J Hepatol,2015,63:156-163.
[15] Bruschi FV, Claudel T, Tardelli M, et al. PNPLA3 I148M variant impairs liver X receptor signaling and cholesterol homeostasis in human hepatic stellate cells. Hepatol Commun,2019,3:1191-1204.
[16] Lampidonis AD, Rogdakis E, Voutsinas GE, et al.The resurgence of hormone-sensitive lipase (HSL) in mammalian lipolysis. Gene,2011,477:1-11.
[17] Albert JS, Yerges-Armstrong LM, Horenstein RB, et al. Null mutation in hormonesensitive lipase gene and risk of type 2 diabetes. N Engl J Med,2014,370:2307-2315.
[18] Douglass JD, Zhou YX, Wu A, et al. Global deletion of MGL in mice delays lipid absorption and alters energy homeostasis and diet-induced obesity. J Lipid Res,2015, 56:1153-1171.
[19] Xiang W, Shi R, Kang X, et al. Monoacylglycerol lipase regulates cannabinoid receptor 2-dependent macrophage activation and cancer progression. Nat Commun, 2018,9:2574.
[20] Habib A, Chokr D, Wan J, et al. Inhibition of monoacylglycerol lipase, an anti-inflammatory and antifibrogenic strategy in the liver. Gut, 2019,68:522-532.
[21] Lian J, Nelson R, Lehner R. Carboxylesterases in lipid metabolism: from mouse to human. Protein Cell,2018,9:178-195. |
