肝动脉灌注化疗及其联合治疗在中晚期肝细胞癌中的应用进展

摘要/Abstract

摘要： 肝动脉灌注化疗(hepatic arterial infusion chemotherapy,HAIC)已经被应用于无法切除的中晚期肝细胞癌(hepatocellular carcinoma,HCC)且取得了肯定的疗效,全身毒副作用小。随着索拉非尼(sorafenib)和仑伐替尼(lenvatinib)的应用、肝癌局部治疗(射频消融、放射治疗、TACE等)的进一步发展以及化疗方案的优化,肝动脉灌注化疗在中晚期肝细胞癌中的联合应用迎来了新一轮热潮,针对其安全性和有效性的临床研究逐渐增多。本文将对肝动脉灌注化疗及其联合治疗在中晚期肝细胞癌中的应用现状展开综述。

关键词: 肝细胞癌, 肝动脉灌注化疗, 介入治疗, 局部灌注

刘晓侃, 张超杰, 赵辉. 肝动脉灌注化疗及其联合治疗在中晚期肝细胞癌中的应用进展[J]. 肝脏, 2021, 26(12): 1411-1414.

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