关键词: 肝癌, 微波消融术, 肝动脉化疗栓塞术

Abstract: Objective To observe the therapeutic effect of combining transcatheter arterial chemoembolization (TACE) with ultrasound-guided microwave ablation (MWA) in the treatment of primary liver cancer.Methods We collected data from 96 cases of single primary hepatocellular carcinoma in our hospital over the past two years. In the control group, 46 cases were treated with transcatheter arterial chemoembolization. In the treatment group, 50 cases were treated with transcatheter arterial chemoembolization and ultrasound-guided microwave ablation. We not only compared changes in serum total bilirubin (TBil), alanine aminotransferase (ALT), glutamic grass, transaminase (AST), serum alpha fetoprotein (AFP) before and after surgery, but also analyzed and recurrence of hepatocellular carcinoma within one year.Results The treatment group showed a significant decrease in serum AFP levels and a lower recurrence rate of hepatocellular carcinoma within one year (18.00%) compared to the control group (89.13%) (χ²=48.56, P< 0.05). The levels of serum TBil (t=0.065, P>0.05), ALT (t=0.079, P>0.05) and AST (t=0.076, P>0.05) were similar in both groups when undergoing hepatoprotective treatment.Conclusion The combined treatment of hepatic artery chemoembolization and ultrasound-guided microwave ablation yields significantly better curative results compared to simple hepatic artery chemoembolization, with little influence on liver function. However, patients selection plays a crucial role. It is recommended to perform thorough ablation at one time to minimize risk of intrahepatic and extrahepatic metastasis.

Key words: Liver cancer, Microwave ablation, Transcatheter arterial chemoembolization