慢加急性肝衰竭人工肝、肝移植的分水岭在哪里？

摘要/Abstract

摘要： 目前慢加急性肝衰竭(Acute-on-Chronic Liver Failure,ACLF)的治疗手段主要包括病因治疗、去除诱因、并发症的内科综合治疗,以及人工肝支持治疗、肝移植。肝移植治疗的应用受限于肝源紧缺、费用昂贵等因素,肝移植最佳适用人群的选择一直是ACLF治疗策略中亟需解决的问题;人工肝治疗可以作为ACLF患者接受肝移植治疗前的桥架治疗方式,但是其是否会使ACLF患者生存获益一直存在争议,人工肝治疗的时机、治疗模式的选择同样是ACLF治疗中值得探讨的问题。本文就ACLF患者的人工肝治疗、肝移植治疗决策相关研究进行综述。

关键词: 慢加急性肝衰竭, 人工肝, 肝移植, 分水岭

徐曼曼, 陈煜. 慢加急性肝衰竭人工肝、肝移植的分水岭在哪里？[J]. 肝脏, 2024, 29(10): 1163-1166.

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