临床实践指南闭环自我演进的生态系统——中国临床实践指南联盟的愿景中国临床实践指南联盟白皮书

摘要/Abstract

摘要： 临床实践指南是连接循证证据与临床决策的核心桥梁,但当前其在制定、评价、传播与实施各环节均存在系统性碎片化问题,严重制约了指南的临床实际指导价值。本文以中国临床实践指南联盟(GUIDANCE)的战略框架为基础,提出构建闭环且自我演进的指南生态系统新范式,以“制定-评价-传播-实施-反馈-更新”为持续循环的机制。该范式由四大支柱支撑:效率驱动(智能制定与动态更新)、质量驱动(透明评价与可信度建设)、实施驱动(智能传播与临床可及性)以及需求驱动(反馈整合与人才培养)。各支柱均涉及需要针对性解决的核心痛点、应对举措与预期成效,相互之间需要适当的协同强化机制。上述框架代表着临床实践指南从单纯制定向系统建设的范式转变,为中国乃至国际临床指南管理体系的改革提供了可行的操作路径。

关键词: 临床实践指南, 指南生态系统, 动态指南, 循证医学, 实施科学, 指南方法学, 闭环管理

夏君, 王吉耀, 瞿介明, 陈诗卉. 临床实践指南闭环自我演进的生态系统——中国临床实践指南联盟的愿景中国临床实践指南联盟白皮书[J]. 肝脏, 2026, 31(6): 768-773.

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