生活方式影响代谢功能障碍相关脂肪性肝病的研究现况

摘要/Abstract

摘要： 代谢功能障碍相关脂肪性肝病(MASLD)与现代生活方式密切相关,本文综述了饮食、运动、睡眠及心理因素四个方面对MASLD的影响。西方膳食模式增加患病风险,而地中海饮食和咖啡摄入具有保护作用;久坐是独立危险因素,有氧与力量训练可直接改善肝脏脂肪变性,且不依赖于体质量下降;睡眠时长与MASLD风险呈U形关系,阻塞性睡眠呼吸暂停综合征和昼夜节律失调加剧肝损伤;慢性心理压力与MASLD互相影响形成恶性循环。单一维度干预效果有限,整合的多学科综合管理策略,是实现肝脏代谢和整体健康系统性改善的最根本手段。

刘毓骁, 朱传龙. 生活方式影响代谢功能障碍相关脂肪性肝病的研究现况[J]. 肝脏, 2026, 31(6): 919-922.

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