Diagnostic value of 3.0-T diffusion-weighted magnetic resonance imaging combined with contrast-enhanced ultrasound in benign and malignant liver lesions

Abstract

Abstract: Objective To analyze the diagnostic effect of 3.0T magnetic resonance diffusion-weighted imaging (MRI-DWI) combined with contrast-enhanced ultrasound in benign and malignant liver lesions.Methods We conducted a retrospective analysis of clinical data from 69 patients with hepatic space-occupying lesions who were admitted to the hospital from February 2020 to July 2022. All patients underwent 3.0TMRI-DWI examination, contrast ultrasound examination and pathological examination. The pathological diagnosis results of all patients were recorded. We compared the apparent diffusion coefficient (ADC) values of patients with benign and malignant liver lesions, as well as the contrast-enhanced ultrasound parameters. Pathological diagnosis was taken as the gold standard to analyze the diagnostic efficacy of 3.0TMRI-DWI examination, contrast-enhanced ultrasound examination, and their combined examination for benign and malignant liver lesions.Results Pathological diagnosis results showed that among the 69 patients with liver lesions (85 lesions in total), 38 cases were diagnosed as benign lesions (55.07%, 47 lesions) and 31 cases as malignant lesions (44.93%, 38 lesions). The ADC value in patients with malignant liver lesions was lower than that in patients with benign liver lesions (P<0.05). The peak intensity of liver malignant lesions was higher than that of liver benign lesions (P<0.05), and the disappearance time, onset time and peak time of liver malignant lesions were shorter than those of liver benign lesions (P<0.05). The diagnostic accuracy of 3.0T MRI-DWI, contrast-enhanced ultrasound and their combined examination for benign and malignant liver lesions were 82.61%, 68.12% and 94.20%, respectively. The sensitivity values of 3.0T MRI-DWI, contrastus-enhanced ultrasound, and combined tests for detecting benign and malignant liver lesions were 88.87%, 70.97%, 93.55%, while the specificity values were 81.57%, 65.79%, 94.74%, respectively. The kappa values of 3.0T MRI-DWI examination, contrastus-enhanced ultrasound examination, and combined examination for benign and malignant liver lesions and pathological diagnosis were 0.851, 0.727 and 0.873, respectively, indicating good consistency (P<0.05).Conclusion Contrast-enhanced ultrasound and 3.0T MRI-DWI can be used in the diagnosis of benign and malignant liver lesions, and their combination has a higher diagnostic value.

Key words: 3.0T magnetic resonance diffusion-weighted imaging, Contrast-enhanced ultrasound, Benign and malignant liver lesions, Diagnostic value

LIU Yang-yang, YANG Xing-xing, GE Shu. Diagnostic value of 3.0-T diffusion-weighted magnetic resonance imaging combined with contrast-enhanced ultrasound in benign and malignant liver lesions[J]. Chinese Hepatolgy, 2023, 28(11): 1310-1313.

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