Abstract: Objective To explore the effectiveness and value of magnetic resonance cholangiopancreatography (MRCP) combined with multi row spiral CT in the diagnosis of malignant biliary obstruction. Methods 82 patients with malignant biliary obstruction who received treatment at Suzhou Integrated Traditional Chinese and Western Medicine Hospital from March 2019 to September 2023 were selected. All of the patients had underwent MRCP and multi row spiral CT examinations. The differences in bile duct display ability between MRCP and multi row spiral CT, compare the imaging features of patients with MRCP and multi row spiral CT, including biliary stricture, tumor obstruction, and surrounding liver tissue involvement, and analyze the differences in localization diagnosis results between the two methods were compared; Receiver operating characteristic curve (ROC) was performed to analyze the value and accuracy of MRCP, multi slice spiral CT, and their combination in the diagnosis of malignant biliary obstruction. Results The average bile duct display ability of MRCP was 4.23°, which was 4.01° of multi row spiral CT; In the imaging images of malignant biliary obstruction, both groups showed irregular thickening of the bile duct wall accompanied by retrograde intrahepatic bile duct dilation; The main manifestation of vascular invasion was stenosis or occlusion; Lymph node metastasis often manifested as an increase in short diameter or enhancement in a circular or circular shape; The manifestation of organ invasion was unclear boundary and low-density necrotic lesion. Two methods showed differences in biliary stenosis and tumor obstruction, but both had high consistency with clinical diagnostic results; ROC analysis showed that, MRCP、 The AUC for the diagnosis of malignant biliary obstruction using multi row spiral CT and their combination were 0.889, 0.870, and 0.948, respectively; The corresponding sensitivities were 87.80%, 93.80%, and 97.78%. Conclusion Magnetic resonance cholangiopancreatography (MRCP) combined with multi row spiral CT had significant diagnostic value in the diagnosis of malignant biliary obstruction, which could significantly improve its diagnostic accuracy. It is worthy to be widely used in clinical practice.

Key words: Magnetic resonance cholangiopancreatography technology, Multi row spiral CT, Malignant biliary obstruction