氩气刀用于肝癌术中残肝断面处理对术后复发及生存率的影响

摘要/Abstract

摘要： 目的研究氩气刀用于肝癌术中残肝断面处理对术后复发及生存率的影响。方法纳入2014年1月至2016年8月于我院收治的144例肝癌患者为对象,均行非根治性姑息切除手术,术中均予以肝门阻断处理。按照抽签随机方法分为两组,各72例,其中对照组采用传统电刀行残肝断面处理,观察组采用氩气刀行残肝断面处理。分析两组术中及术后情况(残肝断面面积、手术时间、术中失血量、术中输血量、肝门阻断时间及术后引流液总量、引流天数、住院时间),比较两组术后6个月及1、2、3年生存率,并观察术后6、9个月及1、2年复发率。结果观察组术中失血量及输血量显著低于对照组(P<0.05)。观察组术后6个月、1年、2年和3年生存率分别为91.67%、62.50%、27.78%和13.89%,显著高于对照组的79.17%、45.83%、12.50%和8.33%(P<0.05)。观察组术后6个月、9个月、1年和2年复发率分别为31.94%、63.89%、77.78%、86.11%,显著低于对照组的58.33%、79.17%、90.28%和95.83%(P<0.05)。结论肝癌切除术中采用氩气刀行残肝断面处理,能降低术中失血量及输血量,减少肿瘤复发,提高患者生存率。

关键词: 氩气刀, 肝癌, 残肝断面处理, 复发, 生存率

Abstract: Objective To study the effect of argon knife dealing with liver cross section in hepatic resection for hepatocellular carcinoma on postoperative recurrence and survival rate. Methods A total of 144 patients with hepatocellular carcinoma admitted to our hospital from January 2014 to August 2016 received non-radical palliative resection and hepatic portal occlusion. The patients were randomly divided into 2 groups, 72 in each. The liver cross section was treated with traditional electric knife in the control group and argon knife in the observation group. The intraoperative and postoperative conditions (the residual hepatic cross section area, operation time, intraoperative blood loss, intraoperative blood transfusion volume, hepatic portal occlusion time, the total postoperative drainage volume, drainage days, and the postoperative hospital stay time) of the 2 groups were analyzed. The 6-month, 1-year, 2-year, 3-year survival rate, and 6-month, 9-month, 1-year, 2-year recurrence rate after operation were compared between the 2 groups. Results The intraoperative blood loss and transfusion volume in the observation group were significantly less than those in the control group (P<0.05). The postoperative 6-month, 1-year, 2-year and 3-year survival rates in the observation group were 91.67%, 62.50%, 27.78% and 13.89%, respectively, which were significantly higher than those in the control group (79.17%, 45.83%, 12.50% and 8.33%, respectively, P<0.05). The 6-month, 9-month, 1-year and 2-year recurrence rates after operation in the observation group were 31.94%, 63.89%, 77.78% and 86.11%, which were significantly lower than those in the control group (58.33%, 79.17%, 90.28% and 95.83%, respectively, P<0.05). Conclusion In the resection for hepatocellular carcinoma, argon knife can reduce the intraoperative blood loss and blood transfusion, lower the tumor recurrence, and improve the survival rate of patients.

Key words: Argon knife, Liver cancer, Surgical treatment of the liver cross section, Recurrence, Survival rate

李得福, 夏永红, 马英. 氩气刀用于肝癌术中残肝断面处理对术后复发及生存率的影响[J]. 肝脏, 2020, 25(8): 819-821.

LI De-fu, XIA Yong-hong, MA Ying. Effect of argon knife in hepatic resection for hepatocellular carcinoma on postoperative recurrence and survival rate[J]. Chinese Hepatolgy, 2020, 25(8): 819-821.

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氩气刀用于肝癌术中残肝断面处理对术后复发及生存率的影响

Effect of argon knife in hepatic resection for hepatocellular carcinoma on postoperative recurrence and survival rate

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