乙型肝炎病毒基因型及其临床意义的研究进展

摘要/Abstract

摘要： 乙型肝炎病毒(Hepatitis B Virus, HBV)以全基因序列的差异可以分为不同的基因型与基因亚型。不同基因型/基因亚型之间可以出现重组,产生重组亚型。不同基因型HBV的分布有明显的地域聚集性,其生物学特性也存在差异。HBV基因型与慢性HBV感染的自然病程和抗病毒治疗反应等也密切相关。通过对HBV基因型进行研究,了解不同基因型HBV感染的流行病学特征,临床特点及预后,可有助于临床医生制定精准化的预防和治疗策略。

关键词: 乙型肝炎病毒, 基因型, 分子流行病学, 临床特征, 精准防治

杜凌遥, 马元吉, 吕朵朵, 唐红. 乙型肝炎病毒基因型及其临床意义的研究进展[J]. 肝脏, 2021, 26(9): 1044-1046.

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