3.0T磁共振扩散加权成像结合超声造影对肝脏良恶性病变的诊断价值

肝脏 ›› 2023, Vol. 28 ›› Issue (11): 1310-1313.

3.0T磁共振扩散加权成像结合超声造影对肝脏良恶性病变的诊断价值

刘洋洋, 杨星星, 葛舒

226002 江苏南通市第二人民医院影像科(刘洋洋,杨星星);南通市肿瘤医院超声科(葛舒)

收稿日期:2023-07-27 出版日期:2023-11-30 发布日期:2024-03-03
通讯作者: 杨星星,Email:ny2yyxx@163.com
基金资助:
南通市科学科技计划项目(JCZ20085)

Diagnostic value of 3.0-T diffusion-weighted magnetic resonance imaging combined with contrast-enhanced ultrasound in benign and malignant liver lesions

LIU Yang-yang¹, YANG Xing-xing¹, GE Shu²

1. Department of Imaging, Nantong Second People's Hospital, Jiangsu 226002, China;
2. Department of Ultrasound, Nantong Cancer Hospital, Jiangsu 226000, China

Received:2023-07-27 Online:2023-11-30 Published:2024-03-03
Contact: YANG Xing-xing,Email:ny2yyxx@163.com

摘要/Abstract

摘要： 目的分析3.0T磁共振扩散加权成像(MRI-DWI)结合超声造影应用于肝脏良恶性病变中的诊断效果。方法选择2020年2月至2022年7月就诊的肝脏占位性病变患者69例。所有患者均采用3.0TMRI-DWI、超声造影及病理检查,比较肝脏良性病变与肝脏恶性病变患者表观弥散系数(ADC)值和病灶的超声造影参数。分析3.0TMRI-DWI、超声造影及二者联合检查对肝脏良恶性病变的诊断效能。结果 69例肝脏占位性病变患者中肝脏良性病变38例(55.07%,共有47个病灶),肝脏恶性病变31例(44.93%,共有38个病灶)。肝脏恶性病变患者ADC值比肝脏良性病变患者低(P<0.05)。肝脏恶性病灶峰值强度比肝脏良性病灶高(P<0.05),肝脏恶性病灶始消时间、始增时间及达峰时间均比肝脏良性病灶短(P<0.05)。3.0TMRI-DWI检查、超声造影检查及二者联合检查诊断肝脏良恶性病变的准确率分别为82.61%、68.12%、94.20%,灵敏度分别为88.87%、70.97%、93.55%、特异度分别为81.57%、65.79%、94.74%,与病理诊断的Kappa值分别为0.851、0.727、0.873,具有较好的一致性(P<0.05)。结论超声造影检查、3.0TMRI-DWI检查可用于诊断肝脏良恶性病变,且二者联合具有更高的诊断价值。

关键词: 3.0T磁共振扩散加权成像, 超声造影, 肝脏良恶性病变, 诊断价值

Abstract: Objective To analyze the diagnostic effect of 3.0T magnetic resonance diffusion-weighted imaging (MRI-DWI) combined with contrast-enhanced ultrasound in benign and malignant liver lesions.Methods We conducted a retrospective analysis of clinical data from 69 patients with hepatic space-occupying lesions who were admitted to the hospital from February 2020 to July 2022. All patients underwent 3.0TMRI-DWI examination, contrast ultrasound examination and pathological examination. The pathological diagnosis results of all patients were recorded. We compared the apparent diffusion coefficient (ADC) values of patients with benign and malignant liver lesions, as well as the contrast-enhanced ultrasound parameters. Pathological diagnosis was taken as the gold standard to analyze the diagnostic efficacy of 3.0TMRI-DWI examination, contrast-enhanced ultrasound examination, and their combined examination for benign and malignant liver lesions.Results Pathological diagnosis results showed that among the 69 patients with liver lesions (85 lesions in total), 38 cases were diagnosed as benign lesions (55.07%, 47 lesions) and 31 cases as malignant lesions (44.93%, 38 lesions). The ADC value in patients with malignant liver lesions was lower than that in patients with benign liver lesions (P<0.05). The peak intensity of liver malignant lesions was higher than that of liver benign lesions (P<0.05), and the disappearance time, onset time and peak time of liver malignant lesions were shorter than those of liver benign lesions (P<0.05). The diagnostic accuracy of 3.0T MRI-DWI, contrast-enhanced ultrasound and their combined examination for benign and malignant liver lesions were 82.61%, 68.12% and 94.20%, respectively. The sensitivity values of 3.0T MRI-DWI, contrastus-enhanced ultrasound, and combined tests for detecting benign and malignant liver lesions were 88.87%, 70.97%, 93.55%, while the specificity values were 81.57%, 65.79%, 94.74%, respectively. The kappa values of 3.0T MRI-DWI examination, contrastus-enhanced ultrasound examination, and combined examination for benign and malignant liver lesions and pathological diagnosis were 0.851, 0.727 and 0.873, respectively, indicating good consistency (P<0.05).Conclusion Contrast-enhanced ultrasound and 3.0T MRI-DWI can be used in the diagnosis of benign and malignant liver lesions, and their combination has a higher diagnostic value.

Key words: 3.0T magnetic resonance diffusion-weighted imaging, Contrast-enhanced ultrasound, Benign and malignant liver lesions, Diagnostic value

刘洋洋, 杨星星, 葛舒. 3.0T磁共振扩散加权成像结合超声造影对肝脏良恶性病变的诊断价值[J]. 肝脏, 2023, 28(11): 1310-1313.

LIU Yang-yang, YANG Xing-xing, GE Shu. Diagnostic value of 3.0-T diffusion-weighted magnetic resonance imaging combined with contrast-enhanced ultrasound in benign and malignant liver lesions[J]. Chinese Hepatolgy, 2023, 28(11): 1310-1313.

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