MRI Dual Lava动脉早晚期结合门脉期增强扫描技术在诊断肝癌中的应用

摘要/Abstract

摘要： 目的探讨磁共振成像(MRI) Dual 肝脏容积快速三维成像(Lava)动脉早晚期结合门脉期增强扫描技术在诊断原发性肝癌中的价值。方法回顾性分析2021年1月至2021年12月行MRI检查的393例肝脏占位性病变患者临床资料。比较MRI影像检查结果与病理检查结果。观察肝脏病变患者MRI检查影像学特征。分析MRI Dual Lava技术对肝癌的诊断价值。结果 393例患者中病理检查诊断为肝癌共55例,检出率为13.99%。经MRI Lava动脉早晚期结合门脉期增强扫描共检出358个病灶,检出率为91.09%,其中检出肝癌46个、肝脏良性病变312个。肝癌患者MRI扫描结果中Dual Lava动脉期阳性检出率高于T1WI、T2WI、延迟期及门静脉期(χ²=4.398、8.731、7.566、11.210,P=0.036、0.003、0.006、0.001)。MRI Dual Lava技术对肝癌进行诊断的灵敏度为83.63%(95%CI:70.69%~91.79%)、特异度为92.30%(95%CI:88.80%~94.82%)、准确度为91.09%(95%CI:87.72%~93.64%)、AUC为0.850(95%CI:0.842~0.915)。结论 MRI Dual Lava技术对肝癌的诊断价值较高。

关键词: 肝癌, 诊断, 磁共振成像, 肝脏容积快速三维成像, 动脉期, 门静脉期

Abstract: Objective To investigate the value of magnetic resonance imaging (MRI) Dual liver volume rapid three-dimensional imaging (Lava) early and late arterial phases combined with portal phase contrast-enhanced scanning in the diagnosis of liver cancer. Methods The clinical data of 393 patients with liver space-occupying lesions who underwent MRI examination in the hospital from January 2021 to December 2021 were retrospectively analyzed. Pathological examination results were recorded. The MRI imaging findings were compared with the pathological findings. The imaging features of MRI imaging in patients with liver disease were observed. The diagnostic value of MRI Dual Lava arterial early and late arterial phases combined with portal phase contrast-enhanced scanning technology for liver cancer was analyzed by Receiver operating characteristic curve (ROC) method. Results Among the 393 lesions, 55 lesions were diagnosed as liver cancer by pathological examination, and the detection rate was 13.99%. A total of 358 lesions were detected by MRI Lava early and late arterial phases combined with portal venous phase contrast-enhanced scanning, with a detection rate of 91.09%, including 46 liver cancers and 312 benign liver lesions. Dual Lava showed marked enhancement in arterial phase, decreased signal in portal venous phase and delayed phase, and "pseudocapsule" signs were seen. The positive detection rate of Dual Lava arterial phase in MRI scan results of liver cancer patients was higher than those of T1W1, T2W1, delayed phase, and protal venous phase (=4.398, 8.731, 7.566, 11.210, P=0.036, 0.003, 0.006, 0.001). The sensitivity of MRI Dual Lava technology for diagnosing liver cancer was 83.63% (95%CI: 70.69%~91.79%), the specificity was 92.30% (95%CI: 88.80%~94.82%), and the accuracy was 91.09% (95%CI: 87.72%~93.64%), the area under the curve (AUC) was 0.850 (95%CI: 0.842~0.915). Conclusion MRI Dual Lava arterial early and late phases combined with portal venous phase contrast-enhanced scanning has high diagnostic value for liver cancer.

Key words: Liver cancer, Diagnosis, Magnetic resonance imaging, Rapid three-dimensional imaging of liver volume, Arterial phase, Portal venous phase

杨莉月, 杨晓亮, 殷慧康. MRI Dual Lava动脉早晚期结合门脉期增强扫描技术在诊断肝癌中的应用[J]. 肝脏, 2023, 28(6): 673-675.

YANG Li-yue, YANG Xiao-liang, YIN Hui-kang. Application of MRI Dual Lava early and late arterial phases combined with portal phase contrast-enhanced scanning in the diagnosis of liver cancer[J]. Chinese Hepatolgy, 2023, 28(6): 673-675.

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