“口-肠-肝轴”在非酒精性脂肪性肝病中的作用

摘要/Abstract

摘要： 非酒精性脂肪性肝病(non-alcoholic fatty liver disease, NAFLD)是最主要的慢性肝病之一,发病率逐年增加,然其发病机制尚未完全阐明。近年来研究表明,口腔炎症、口腔菌群是NAFLD的危险因素之一。牙龈卟啉单胞菌等口腔菌群通过直接影响肝脏细胞功能、破坏肠道稳态等途径促进NAFLD的发生和发展。本文主要针对“口-肠-肝轴”在NAFLD中的作用机制及治疗应用进行综述。

关键词: 非酒精性脂肪性肝病, 口-肠-肝轴, 口腔菌群, 牙龈卟啉单胞菌

陈璐, 杨妙芳, 汪芳裕. “口-肠-肝轴”在非酒精性脂肪性肝病中的作用[J]. 肝脏, 2024, 29(1): 110-113.

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