白细胞介素-6在原发性肝癌中的研究进展

摘要/Abstract

摘要： 肝细胞癌(HCC)是世界范围内常见的恶性肿瘤,病死率很高。HCC发病机制复杂,涉及多种因素,包括慢性炎症、乙型和丙型肝炎病毒感染、饮酒等。最近的研究表明,白细胞介素-6(IL-6)在HCC中具有关键作用,既促进肝癌细胞的增殖和转移,又限制了细胞的凋亡反应。本文综述了近年来IL-6在HCC中的研究进展,包括其对HCC的生物学意义、作为 HCC 预后的生物标志物的潜力及其治疗意义。我们还介绍了 HCC 中 IL-6 研究的挑战和未来方向,这可能为 HCC 新型靶向疗法的开发提供参考。

刘敏, 李莉. 白细胞介素-6在原发性肝癌中的研究进展[J]. 肝脏, 2024, 29(1): 122-126.

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