[1] Brunt Em, Wong Vw, Nobili V, et al. Nonalcoholic fatty liver disease [J]. Nat Rev Dis Primers, 2015, 1: 15080. [2] Wong Vw, Wong Gl, Chan Rs, et al. Beneficial effects of lifestyle intervention in non-obese patients with [J]. J Hepatol, 2018, 69(6): 1349-1356. [3] Wei Jl, Leung Jc, Loong Tc, et al. Prevalence and Severity of Nonalcoholic Fatty Liver Disease in Non-Obese [J]. Am J Gastroenterol, 2015, 110(9): 1306-1314. [4] Kim D, Kim Wr. Nonobese Fatty Liver Disease [J]. Clin Gastroenterol Hepatol, 2017, 15(4): 474-485. [5] Golabi P, Paik J, Fukui N, et al. Patients With Lean Nonalcoholic Fatty Liver Disease Are Metabolically Abnormal [J]. Clin Diabetes, 2019, 37(1): 65-72. [6] Lu Fb, Zheng Ki, Orcid Id, et al. Global epidemiology of Lean non-alcoholic fatty liver disease: A systematic [J]. J Gastroenterol Hepatol, 2020, 35(12): 2041-2050. [7] Wang Q, You H, Ou X, et al. Non-obese histologically confirmed NASH patients with abnormal liver biochemistry [J]. Hepatol Int, 2019, 13(6): 766-776. [8] Maier S, Orcid Id, Wieland A, et al. Lean NAFLD: an underrecognized and challenging disorder in medicine [J]. Rev Endocr Metab Disord, 2021, 22(2): 351-366. [9] Young S, Tariq R, Provenza J, et al. Prevalence and Profile of Nonalcoholic Fatty Liver Disease in Lean Adults [J]. Hepatol Commun, 2020, 4(7): 953-972. [10] Younossi Zm, Stepanova M, Negro F, et al. Nonalcoholic fatty liver disease in Lean individuals in the United States [J]. Medicine (Baltimore), 2012, 91(6): 319-327. [11] Das K, Das K, Mukherjee Ps, et al. Nonobese population in a developing country has a high prevalence of nonalcoholic [J]. Hepatology, 2010, 51(5): 1593-1602. [12] Kwon Ym, Oh Sw, Hwang Ss, et al. Association of nonalcoholic fatty liver disease with components of metabolic [J]. Am J Gastroenterol, 2012, 107(12): 1852-1858. [13] Sinn Dh, Gwak Gy, Park Hn, et al. Ultrasonographically detected non-alcoholic fatty liver disease is an independent [J]. Am J Gastroenterol, 2012, 107(4): 561-567. [14] Choudhary Ns, Saraf N, Saigal S, et al. Nonalcoholic Fatty Liver in Lean Individuals: Clinicobiochemical Correlates of [J]. J Clin Exp Hepatol, 2021, Sep-Oct; 11(5): 544-549. [15] Wu Y, Zheng Q, Zou B, et al. The epidemiology of NAFLD in Mainland China with analysis by adjusted gross [J]. Hepatol Int, 2020, 14(2): 259-269. [16] Amarapurkar Dn, Hashimoto E, Lesmana La, et al. How common is non-alcoholic fatty liver disease in the Asia-Pacific region and [J]. J Gastroenterol Hepatol, 2007, 22(6): 788-793. [17] Wang Ay, Dhaliwal J, Mouzaki M. Lean non-alcoholic fatty liver disease [J]. Clin Nutr, 2019, 38(3): 975-981. [18] Vilarinho S, Ajmera V, Orcid Id, et al. Emerging Role of Genomic Analysis in Clinical Evaluation of Lean Individuals With [J]. Hepatology, 2021, 74(4): 2241-2250. [19] Meroni M, Orcid Id, Longo M, et al. Genetics Is of the Essence to Face NAFLD [J]. Biomedicines, 2021, 9(10): 1359. [20] Pingitore P, Romeo S. The role of PNPLA3 in health and disease [J]. Biochim Biophys Acta Mol Cell Biol Lipids, 2019, 1864(6): 900-906. [21] Honda Y, Yoneda M, Kessoku T, et al. Characteristics of non-obese non-alcoholic fatty liver disease: Effect of genetic [J]. Hepatol , 2016, 46(10): 1011-1018. [22] Fracanzani Al, Petta S, Lombardi R, et al. Liver and Cardiovascular Damage in Patients With Lean Nonalcoholic Fatty Liver [J]. Clin Gastroenterol Hepatol, 2017, 15(10): 1604-1611. [23] Treiber G, Flaus Furmaniuk A, Orcid Id, et al. A recurrent familial partial lipodystrophy due to a monoallelic or biallelic LMNA [J]. Eur J Endocrinol, 2021, 185(4): 453-462. [24] Hsu Cl, Wu Fz, Lin Kh, et al. Role of Fatty Liver Index and Metabolic Factors in the Prediction of Nonalcoholic [J]. Clin Transl Gastroenterol, 2019, 10(5): 1-8. [25] Zhang X, Liu S, Dong Q, et al. The Genetics of Clinical Liver Diseases: Insight into the TM6SF2 E167K Variant [J]. J Clin Transl Hepatol, 2018, 6(3): 326-331. [26] Angulo P, Kleiner De, Dam-Larsen S, et al. Liver Fibrosis, but No Other Histologic Features, Is Associated With Long-term [J]. Gastroenterology, 2015, 149(2): 389-397. [27] Patel Ya, Orcid Id, Gifford Ej, et al. Risk factors for biopsy-proven advanced non-alcoholic fatty liver disease in the [J]. Aliment Pharmacol Ther, 2018, 47(2): 268-278. [28] Kim Hj, Kim Hj, Lee Ke, et al. Metabolic significance of nonalcoholic fatty liver disease in nonobese [J]. Arch Intern Med, 2004, 164(19): 2169-2175. [29] Bugianesi E, Moscatiello S, Ciaravella Mf, et al. Insulin resistance in nonalcoholic fatty liver disease [J]. Curr Pharm Des, 2010, 16(17): 1941-1951. [30] Leung Jc, Loong Tc, Wei Jl, et al. Histological severity and clinical outcomes of nonalcoholic fatty liver disease [J]. Hepatology, 2017, 65(1): 54-64. [31] Akyuz U, Yesil A, Yilmaz Y. Characterization of Lean patients with nonalcoholic fatty liver disease [J]. Scand J Gastroenterol, 2015, 50(3): 341-346. [32] Bernhardt P, Kratzer W, Schmidberger J, et al. Laboratory parameters in Lean NAFLD: comparison of subjects with Lean NAFLD withobese subjects without hepatic steatosis [J]. BMC Res Notes, 2018, 11(1): 101. [33] Hagström H, Nasr P, Ekstedt M, et al. Risk for development of severe liver disease in Lean patients with nonalcoholic [J]. Hepatol Commun, 2017, 2(1): 48-57. [34] Denkmayr L, Feldman A, Stechemesser L, et al. Lean Patients with Non-Alcoholic Fatty Liver Disease Have a Severe Histological [J]. J Clin Med, 2018, 7(12): 562. [35] Nobili V, Cutrera R, Liccardo D, et al. Obstructive sleep apnea syndrome affects liver histology and inflammatory cell [J]. Am J Respir Crit Care Med, 2014, 189(1): 66-76. [36] Alam S, Gupta Ud, Alam M, et al. Clinical, anthropometric, biochemical, and histological characteristics of nonobese nonalcoholic fatty liver disease patients of Bangladesh[J]. Indian J Gastroenterol, 2014, 33(5): 452-457. [37] Fu C, Wai Jw, Nik Mustapha Nr, et al. Performance of Simple Fibrosis Scores in Nonobese Patients With Nonalcoholic [J]. Clin Gastroenterol Hepatol, 2020, (12): 2843-2845. [38] Wong Vw, Tak Wy, Goh Gbb, et al. Performance of Noninvasive Tests of Fibrosis Among Asians, Hispanic, and [J]. Clin Gastroenterol Hepatol, 2023, 21(1): 90-102. [39] Hagström H, Talbäck M, Andreasson A, et al. Repeated FIB-4 measurements can help identify individuals at risk of severe liver [J]. J Hepatol, 2020, 73(5): 1023-1029. [40] Zhang X, Wong Gl, Wong Vw. Application of transient elastography in nonalcoholic fatty liver disease [J]. Clin Mol Hepatol, 2020, 26(2): 128-141. [41] Wong Vw, Irles M, Wong Gl, et al. Unified interpretation of liver stiffness measurement by M and XL probes in [J]. Gut, 2019, 68(11): 2057-2064. [42] Wong Vw, Chan Rs, Wong Gl, et al. Community-based lifestyle modification programme for non-alcoholic fatty liver [J]. J Hepatol, 2013, 59(3): 536-542. [43] Vilar-Gomez E, Martinez-Perez Y, Calzadilla-Bertot L, et al. Weight Loss Through Lifestyle Modification Significantly Reduces Features of [J]. Gastroenterology, 2015, 149(2): 367-e15. |