瘦型非酒精性脂肪性肝病的研究进展

摘要/Abstract

摘要： 随着肥胖在全球范围流行,非酒精性脂肪性肝病(NAFLD)已成为目前全世界慢性肝病的首要病因。近年来的研究发现,约40.8%NAFLD患者的体重指数(BMI)是正常甚至偏瘦的,称为瘦型(非肥胖型)NAFLD。与肥胖型NAFLD相比,瘦型NAFLD患者总体上具有较好的代谢特征,但仍会出现不良的远期预后。从发病因素看,瘦型NAFLD可能存在特殊的发病机制,如脂肪营养不良、肌少症、肠道菌群改变等。本文概述了瘦型NAFLD的研究进展,重点总结了其临床特征、发病因素和预后,为这一特殊类型疾病的诊断和评估提供新的思路。

关键词: 瘦型非酒精性脂肪性肝病, 脂肪营养不良, 肌少症, 肠道菌群

黄浩华, 谢青, 王晓琳. 瘦型非酒精性脂肪性肝病的研究进展[J]. 肝脏, 2024, 29(12): 1568-1573.

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