[1] Feng D, Guan Y, Wang Y, et al. Characterisation of macrophages in healthy and diseased livers in mice: identification of necrotic lesion-associated macrophages[J]. eGastroenterology, 2025, 3: e100189. [2] Ait Ahmed Y, Lafdil F, Tacke F. Ambiguous pathogenic roles of macrophages in alcohol-associated liver diseases[J]. Hepat Med, 2023, 15: 113-127. [3] Krenkel O, Tacke F. Liver macrophages in tissue homeostasis and disease[J]. Nat Rev Immunol, 2017, 17(5): 306-321. [4] Xu Y, Hillman H, Chang M, et al. Identification of conserved and tissue-restricted transcriptional profiles for lipid associated macrophages (LAMs)[J]. bioRxiv, 2024: 2024.09.24.614807. [5] Ramachandran P, Dobie R, Wilson-Kanamori JR, et al. Resolving the fibrotic niche of human liver cirrhosis at single-cell level[J]. Nature, 2019, 575(7783): 512-518. [6] Remmerie A, Martens L, Thoné T, et al. Osteopontin expression identifies a subset of recruited macrophages distinct from Kupffer cells in the fatty liver[J]. Immunity, 2020, 53(3): 641-657.e14. [7] Zhang C, Li J, Cheng Y, et al. Single-cell RNA sequencing reveals intrahepatic and peripheral immune characteristics related to disease phases in HBV-infected patients[J]. Gut, 2023, 72(1): 153-167. [8] Sun J, Zhao P, Shi Y, et al. Recent insight into the role of macrophage in alcohol-associated liver disease: a mini-review[J]. Front Cell Dev Biol, 2023, 11: 1292016. [9] Lewis S A, Doratt B M, Qiao Q, et al. Integrated single cell analysis shows chronic alcohol drinking disrupts monocyte differentiation in the bone marrow[J]. Stem Cell Reports, 2023, 18(9): 1884-1897. [10] Bala S, Csak T, Saha B, et al. The pro-inflammatory effects of miR-155 promote liver fibrosis and alcohol-induced steatohepatitis[J]. J Hepatol, 2016, 64(6): 1378-1387. [11] Momen-Heravi F, Catalano D, Talis A, et al. Protective effect of LNA-anti-miR-132 therapy on liver fibrosis in mice[J]. Mol Ther Nucleic Acids, 2021, 25: 155-167. [12] Wan Y, Slevin E, Koyama S, et al. miR-34a regulates macrophage-associated inflammation and angiogenesis in alcohol-induced liver injury[J]. Hepatol Commun, 2023, 7: e0089. [13] Yang Y, Jia X, Qu M, et al. Exploring the potential of treating chronic liver disease targeting the PI3K/Akt pathway and polarization mechanism of macrophages[J]. Heliyon, 2023, 9(5): e17116. [14] Zhao Y X, Sun Y Y, Li L Y, et al. Rab11b promotes M1-like macrophage polarization by restraining autophagic degradation of NLRP3 in alcohol-associated liver disease[J]. Acta Pharmacol Sin, 2024, 46(1): 134-146. [15] Lu S, Jin H, Nong T, et al. Hepatocyte-derived Fetuin-A promotes alcohol-associated liver disease in mice by inhibiting autophagy-lysosome degradation of TLR and M2 macrophage polarization[J]. Free Radic Biol Med, 2024, 224: 506-520. [16] Cao L, Wu D, Qin L, et al. Single-cell RNA transcriptome profiling of liver cells of short-term alcoholic liver injury in mice[J]. Int J Mol Sci, 2023, 24(5): 4344. [17] Blériot C, Barreby E, Dunsmore G, et al. A subset of Kupffer cells regulates metabolism through the expression of CD36[J]. Immunity, 2021, 54(9): 2101-2116.e6. [18] Sasaki K, Rooge S, Gunewardena S, et al. Kupffer cell diversity maintains liver function in alcohol-associated liver disease[J]. Hepatology, 2025, 81(3): 870-887. [19] Zhao X, Wang S, Liu Q, et al. Single-cell landscape of the intrahepatic ecosystem in alcohol-related liver disease[J]. Clin Transl Med, 2025, 15: e70198. [20] Gao C, Wang S, Xie X, et al. Single-cell profiling of intrahepatic immune cells reveals an expansion of tissue-resident cytotoxic CD4+ T lymphocyte subset associated with pathogenesis of alcoholic-associated liver diseases[J]. Cell Mol Gastroenterol Hepatol, 2025, 19: 101411. [21] Patel F, Parwani K, Patel D, et al. Metformin and probiotics interplay in amelioration of ethanol-induced oxidative stress and inflammatory response in an in vitro and in vivo model of hepatic injury[J]. Mediators Inflamm, 2021, 2021: 1-31. [22] Gu Z, Li F, Liu Y, et al. Exosome-like nanoparticles from Lactobacillus rhamnosus GG protect against alcohol-associated liver disease through intestinal aryl hydrocarbon receptor in mice[J]. Hepatol Commun, 2021, 5(5): 846-864. [23] Sehrawat T S, Liu M, Shah V H. The knowns and unknowns of treatment for alcoholic hepatitis[J]. Lancet Gastroenterol Hepatol, 2020, 5(5): 494-506. [24] Ambade A, Lowe P, Kodys K, et al. Pharmacological inhibition of CCR2/5 signaling prevents and reverses alcohol-induced liver damage, steatosis, and inflammation in mice[J]. Hepatology, 2019, 69(3): 1105-1121. [25] Gao H, Jiang Y, Zeng G, et al. Cell-to-cell and organ-to-organ crosstalk in the pathogenesis of alcohol-associated liver disease[J]. eGastroenterology, 2024, 2: e100104. [26] Duan Y, Chu H, Brandl K, et al. CRIg on liver macrophages clears pathobionts and protects against alcoholic liver disease[J]. Nat Commun, 2021, 12: 7172. |