超声剪切波弹性成像、门静脉血流动力学参数对肝硬化严重程度的评估价值

肝脏 ›› 2026, Vol. 31 ›› Issue (3): 341-344.

超声剪切波弹性成像、门静脉血流动力学参数对肝硬化严重程度的评估价值

刘婷, 杨婉莹, 陈佳锐, 涂娇, 钱嵘

200052 上海中国人民解放军海军第九〇五医院超声诊断科(刘婷,陈佳锐,涂娇,钱嵘),健康管理中心(杨婉莹)

收稿日期:2025-08-02 出版日期:2026-03-31 发布日期:2026-05-19
通讯作者: 钱嵘,Email:2651184151@qq.com
作者简介:共同第一作者:杨婉莹

The evaluation value of ultrasound shear wave elastography and portal vein hemodynamic parameters for the severity of liver cirrhosis

LIU Ting¹, YANG Wan-ying², CHEN Jia-rui¹, TU Jiao¹, QIAN Rong¹

1. Department of Ultrasound, the 905th Naval Hospital, Shanghai 200052, China;
2. Department of Health Management Center, the 905th Naval Hospital, Shanghai 200052, China

Received:2025-08-02 Online:2026-03-31 Published:2026-05-19
Contact: QIAN Rong, Email: 2651184151@qq.com

摘要/Abstract

摘要： 目的探讨超声剪切波弹性成像(SWE)、门静脉血流动力学参数对肝纤维化严重程度的评估价值。方法纳入2024年10月至2025年8月解放军第905医院收治的肝硬化患者66例,其中Child-Pugh A级27例、B级21例、C级18例。选取同期健康体检者24例作为对照组。运用SWE技术测量肝脏SWE平均值(Emean),采用超声CDFI技术检测肝脏门静脉内径(PVD)、静息状态下门静脉流速(PVV)。评估Emean、PVD、PVV与肝硬化Child-Pugh分级的相关性,分析这些参数对评估肝纤维化程度的应用价值。结果 Child-Puch A、B、C级3组患者Emean分别为(9.90±1.64)kPa、(16.84±3.2)kPa、(19.62±6.89)kPa,PVD分别为(11.96±3.6)mm、(13.37±1.2)mm、(13.90±2.81)mm,PVV分别为(14.15±2.12)cm/s、(12.25±1.75)cm/s、(11.07±1.49)cm/s;对照组Emean、PVV、PVD分别为(3.80±0.86)kPa、(10.70±1.7)mm、(19.22±2.14)cm/s,不同肝功能分级患者及对照组Emean、PVD、PVV差异均有统计学意义(F值分别为29.988、4.371、14.078,P<0.05)。肝硬化患者PVD、PVV和肝脏Emean与Child-Pugh分级具有相关性,r分别为0.269、-0.701、0.741。结论肝脏SWE值及门静脉血流动力学指标与肝硬化患者肝纤维化程度关系密切,彩色多普勒超声结合剪切波弹性成像技术对肝硬化患者严重程度具有良好的评估效果。

关键词: 肝硬化, Child-Pugh分级, 剪切波弹性成像, 多普勒超声, 门静脉血流动力学

Abstract: Objective To explore the evaluation value of shear wave elastography (SWE) and portal venous hemodynamic parameters for the severity of liver fibrosis. Methods Sixty-six patients with liver cirrhosis admitted between October 2024 and August 2025 were enrolled in this study. Among them, 27 cases were of Child-Pugh grade A, 21 cases of grade B, and 18 cases of grade C. Additionally, 24 healthy individuals who underwent physical examinations at our hospital were selected as the control group. The average liver SWE (Emean) was measured using SWE technology, and the portal vein diameter (PVD) and resting portal vein velocity (PVV) were detected using ultrasound CDFI technology. By comparing PVD, PVV, and Emean parameters, the correlation between Emean, PVD, PVV, and Child-Pugh score in liver cirrhosis were evaluated, and the application value of these parameters in assessing the degree of liver fibrosis were analyzed. Results The Emean values of the Child-Pugh grade A. B and C groups of patients were (9.90 ± 1.64) kPa, (16.84 ± 3.2) kPa, and (19.62 ± 6.89) kPa, respectively. The PVD values were (11.96 ± 3.6) mm, (13.37 ± 1.2) mm, and (13.90 ± 2.81) mm, respectively. The PVV values were (14.15 ± 2.12) cm/s, (12.25 ± 1.75) cm/s, and (11.07 ± 1.49) cm/s, respectively. There were statistically significant differences in liver Emean, PVV, and PVD between the patients′ groups and the control group (P<0.05), and there were statistically significant differences in liver Emean, PVD, and PVV between patients with different grades of liver function (P<0.05) (F value=29.988, 4.371, 14.078, respectively). PVD, PVV, and liver Emean in patients with cirrhosis are correlated with Child-Pugh grading (correlation coefficients rates=0.269, -0.701, 0.741, respectively). Conclusion Liver SWE and portal vein hemodynamics are closely related to the degree of liver fibrosis in patients with chronic liver diseases. Color doppler ultrasound combined with shear wave elastic imaging technology has a good evaluation efficacy for the severity of liver cirrhosis.

Key words: Cirrhosis, Child-Pugh grading, Shear wave elastography, Doppler ultrasound, Portal vein hemodynamics

刘婷, 杨婉莹, 陈佳锐, 涂娇, 钱嵘. 超声剪切波弹性成像、门静脉血流动力学参数对肝硬化严重程度的评估价值[J]. 肝脏, 2026, 31(3): 341-344.

LIU Ting, YANG Wan-ying, CHEN Jia-rui, TU Jiao, QIAN Rong. The evaluation value of ultrasound shear wave elastography and portal vein hemodynamic parameters for the severity of liver cirrhosis[J]. Chinese Hepatolgy, 2026, 31(3): 341-344.

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