肝脏各型细胞在肝再生中的作用及机制研究进展

摘要/Abstract

摘要： 肝脏具有强大的再生能力,为肝脏损伤修复和维持机体代谢提供了重要保障。肝再生(LR)过程中,实质细胞迅速增殖以弥补细胞缺失;非实质细胞则通过分泌细胞因子、调控炎症等机制,参与调控LR进程。为系统阐释各类型细胞在LR中的作用及机制,本综述聚焦肝细胞(HC)、胆管上皮细胞(BEC)、肝窦内皮细胞(LSEC)、库普弗细胞(KC)及肝星状细胞(HSC),总结其在LR中的功能及其分子机制,为调控LR及肝损伤相关疾病治疗与康复提供文献依据。

关键词: 肝细胞, 胆管上皮细胞, 肝脏非实质细胞, 肝再生

杨启龙, 冉慧杰, 白瑞杰, 迪丽努尔·希尔艾力, 南瑛, 秦绪军. 肝脏各型细胞在肝再生中的作用及机制研究进展[J]. 肝脏, 2026, 31(3): 445-449.

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