肝脏 ›› 2016, Vol. 21 ›› Issue (1): 6-8.

• 论著 • 上一篇    下一篇

血清钠对肝硬化失代偿期患者并发症的影响

舒梦妮, 李树臣   

  1. 150001 哈尔滨医科大学附属第二医院感染科
  • 收稿日期:2015-07-15 发布日期:2020-06-01
  • 通讯作者: 李树臣,Email:shuchenli1964@163.com

Effect of seru Msodiu Mon complications in patients with decompensated liver cirrhosis

SHU Meng-ni, LI Shu-chen   

  1. Second Affiliated Hospital of Harbin Medical University,Departmentof Infectious Diseases,Harbin 150001,China
  • Received:2015-07-15 Published:2020-06-01
  • Contact: LIShu-chen,Email:shuchenli1964@163.com

摘要: 目的 研究血清钠浓度对肝硬化失代偿期患者并发症的影响。方法 对212例肝硬化失代偿期的患者进行回顾性分析,根据患者入院时的血清钠浓度分为正常组和低钠血症组,而低钠血症组又分为轻度、中度、重度组。研究不同浓度的血清钠对肝硬化失代偿期患者并发症的影响。结果 血清钠的浓度越低,发生并发症如:腹水、自发性腹膜炎、肝性脑病的概率越大(消化道出血除外),病死率也越高。正常组、轻度、中度、重度低钠血症组的腹水发生率为33.0%、73.8%、91.4%、100.0%,自发性腹膜炎的发生率为3.5%、14.3%、28.6%、55.0%,肝性脑病的发生率为7.0%、11.9%、28.6%、60.0%,病死率分别为6.1%、11.9%、31.4%、60.0%,正常组的并发症的发生率及病死率明显低于中度、重度组,轻度、中度低钠血症组(P<0.05)。结论 血清钠可作为一个监测指标判定肝硬化失代偿期患者的预后。

关键词: 血清钠, 肝硬化, 并发症, 影响

Abstract: Objective To investigate the effect of seru Msodiu Mlevel on complications in patients with decompensated liver cirrhosis. Methods According to seru Msodiu Mlevel,212 decompensated liver cirrhosis cases were divided into normal group and hyponatremia group(including mild,Moderate and severe subgroups). Sequentially,the influences of different seru Msodiu Mlevels on complications in all enrolled patients were retrospectively analyzed. Results As seru Msodiu Mlevel declined,Mortality and Morbidity were significantly increased because of complications,such as ascites,spontaneous bacterial peritonitis and hepatic encephalopathy(except gastrointestinal bleeding)and so on. The occurrence rates of complications in normal,mild,Moderate and severe groups were 33.0%,73.8%,91.4%,100.0%for ascites,3.5%,14.3%,28.6%,55.0%for spontaneous bacterial peritonitis,7.0%、11.9%、28.6%、60.0%for hepatic encephalopathy,respectively,with Mortality of 6.09%,11.90%,31.43%,60.00%,respectively. Normal group displayed significantly lower complication Morbidity and Mortality than Moderate and severe groups did(P<0.05). Mean w hile,complication Morbidity and Mortality in mild and Moderate group were significantly lower than those in severe group(P<0.05). Conclusion Seru Msodiu Mlevel can be a Monitoring indicator to predict the prognosis of patients with decompensated liver cirrhosis.

Key words: Seru Msodiu m, Liver cirrhosis, complications, Influence