CT对肝硬化各级肝脏血流状态和体积变化规律的评价

摘要/Abstract

摘要： 目的探讨电子计算机断层扫描(CT)对肝硬化各级肝脏血流状态和体积变化规律的应用价值。方法选取我院在2013年12月至2015年12月期间收治符合纳入标准的肝硬化患者25例,使用1972年的Child-Pugh肝功能分级指标,分为A、B、C级,称实验1组、实验2组、实验3组;按照1∶1的匹配,收集正常肝脏人群25例作为对照组。均应用我院CT对肝脏进行体积(LV)测量和灌注成像(PWI),并应用PHILIPS 16层螺旋CT机和CT Perfusion 4对肝硬化患者和对照组的测量和肝脏灌注参数计算,并进行评价,灌注参数包括血流量(BF)、血容量(BV)、平均通过时间(MTT)、肝动脉灌注分数(HAF)。结果与对照组相比,肝硬化患者肝脏灌注的血流量、血容量均降低(F=16.12,P<0.01;F=59.64,P<0.01);平均通过时间延长(F=3.32,P=0.028);肝动脉灌注分数增大(F=48.13,P<0.01);实验1组、实验2组、实验3组的肝体积均减少(P<0.05)。结论 CT能够较准确检测各级肝脏血流状态和体积变化,更好评价肝脏情况。

关键词: 电子计算机断层扫描, 肝体积, 肝灌注参数, 肝硬化

施付强, 朱成良, 朱燕. CT对肝硬化各级肝脏血流状态和体积变化规律的评价[J]. 肝脏, 2016, 21(11): 954-955.

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